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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:impaired behavioral response to nicotine
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Accession:MP:0009756 term browser browse the term
Definition:decreased sensitivity to nicotine resulting in a behavioral response, such as induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response
Synonyms:exact_synonym: impaired behavioural response to nicotine



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impaired behavioral response to nicotine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit IMP RGD PMID:30293722 RGD:14694852 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146
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G Chrna5em18Pas cholinergic receptor, nicotinic, alpha 5 (neuronal); ZFN induced mutant 18,Pas IMP RGD PMID:30293722 RGD:14694852

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Term Annotations click to browse term
  mammalian phenotype 5428
    behavior/neurological phenotype 618
      abnormal behavior 617
        abnormal behavioral response to xenobiotic 141
          impaired behavioral response to xenobiotic 3
            impaired behavioral response to addictive substance 3
              impaired behavioral response to nicotine 3
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