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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:uremia
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Accession:MP:0009644 term browser browse the term
Definition:an excess of urea, creatinine, and other nitrogenous end products of protein and amino acid metabolism in the blood; usually indicative of kidney dysfunction
Synonyms:exact_synonym: azotaemia;   azotemia;   uraemia


show annotations for term's descendants           Sort by:
increased blood urea nitrogen level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anks6 ankyrin repeat and sterile alpha motif domain containing 6 IAGP compared to PKD RGD PMID:7933831 RGD:1300446 NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596 		JBrowse link
G Anks6PKD ankyrin repeat and sterile alpha motif domain containing 6, polycystic kidney disease IAGP compared to PKD RGD PMID:7933831 RGD:1300446
G Cftr CF transmembrane conductance regulator IMP RGD PMID:24608905 RGD:11566051 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cftrem1Sage cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage IMP RGD PMID:24608905 RGD:11566051
G Col4a5 collagen type IV alpha 5 chain IMP RGD PMID:34675305 RGD:329845598 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692 		JBrowse link
G Col4a5em1Matsu collagen type IV alpha 5 chain; CRISPR/Cas9 induced mutant 1, Matsu IMP RGD PMID:34675305 RGD:329845598
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Fh fumarate hydratase IMP RGD PMID:27556703 RGD:13792708 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fhem1 fumarate hydratase; TALEN induced mutant 1 IMP RGD PMID:27556703 RGD:13792708
G Gla galactosidase, alpha onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Glaem2Mcwi galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 IMP RGD PMID:23753405 RGD:13782272 NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796 		JBrowse link
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204 NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702 		JBrowse link
G Kcnj16em1Mcwi potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu IMP RGD PMID:23753405 RGD:13782272
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:30278832 PMID:28746409 RGD:401960095, RGD:401965413 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IMP compared to FHH RGD PMID:24722447 RGD:12910103 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a1m1Mcwi nuclear receptor subfamily 4, group A, member 1; mutation 1, Medical College of Wisconsin IMP compared to FHH RGD PMID:24722447 RGD:12910103
G Ren renin IMP RGD PMID:21242461 RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:21242461 RGD:7771614
G Tmem67 transmembrane protein 67 IAGP RGD PMID:11095650 PMID:15052665 RGD:1300514, RGD:15014788 NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
G Tmem67wpk transmembrane protein 67; wpk mutant IAGP RGD PMID:11095650 PMID:15052665 RGD:1300514, RGD:15014788
G Uox urate oxidase IMP RGD PMID:32368418 RGD:150521544 NCBI chr 2:238,147,130...238,183,320
Ensembl chr 2:235,440,619...235,523,029 		JBrowse link
G Uoxem1Cya urate oxidase; CRISPR/Cas9 induced mutant1, Cya IMP RGD PMID:32368418 RGD:150521544
increased circulating creatinine level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anks6 ankyrin repeat and sterile alpha motif domain containing 6 IAGP compared to PKD RGD PMID:7933831 RGD:1300446 NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596 		JBrowse link
G Anks6PKD ankyrin repeat and sterile alpha motif domain containing 6, polycystic kidney disease IAGP compared to PKD RGD PMID:7933831 RGD:1300446
G Col4a5 collagen type IV alpha 5 chain IMP RGD PMID:34675305 RGD:329845598 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692 		JBrowse link
G Col4a5em1Matsu collagen type IV alpha 5 chain; CRISPR/Cas9 induced mutant 1, Matsu IMP RGD PMID:34675305 RGD:329845598
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Fh fumarate hydratase IMP RGD PMID:27556703 RGD:13792708 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fhem1 fumarate hydratase; TALEN induced mutant 1 IMP RGD PMID:27556703 RGD:13792708
G Lepr leptin receptor IMP RGD PMID:27465994 RGD:12911217 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:27465994 RGD:12911217
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:24244710 RGD:12880447 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:24244710 RGD:12880447
G Ren renin IMP compared to wild type RGD PMID:21242461 RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to wild type RGD PMID:21242461 RGD:7771614
G Sod3 superoxide dismutase 3 onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
G Tmem67 transmembrane protein 67 IAGP RGD PMID:11095650 RGD:1300514 NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
G Tmem67wpk transmembrane protein 67; wpk mutant IAGP RGD PMID:11095650 RGD:1300514
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5428
    homeostasis/metabolism phenotype 1429
      abnormal homeostasis 1330
        abnormal blood homeostasis 767
          uremia 66
            increased blood urea nitrogen level 51
            increased circulating creatinine level 33
paths to the root