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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:epidermis stratum spinosum hyperplasia
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Accession:MP:0009611 term browser browse the term
Definition:increase in the number of normal cells in normal arrangement in the epidermis stratum spinosum, typically resulting in increased size
Synonyms:exact_synonym: hyperplastic epidermal stratum spinosum;   prickle cell layer hyperplasia;   spinous layer hyperplasia
 related_synonym: stratum spinosum hyperplasia


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epidermis stratum spinosum hyperplasia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd5 abhydrolase domain containing 5 IAGP MGI PMID:20023287 NCBI chr 9:122,180,681...122,210,589
Ensembl chr 9:122,180,673...122,210,589 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IAGP MGI PMID:22585574 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Lbr lamin B receptor IEA MGI NCBI chr 1:181,642,880...181,669,933
Ensembl chr 1:181,642,900...181,670,611 		JBrowse link
acanthosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor IAGP MGI PMID:9396142 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 IAGP MGI PMID:29113991 NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409 		JBrowse link
G B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 IAGP MGI PMID:9155011 NCBI chr 4:40,804,602...40,855,711
Ensembl chr 4:40,804,602...40,854,005 		JBrowse link
G Card14 caspase recruitment domain family, member 14 IAGP MGI PMID:29689250 PMID:29980436 NCBI chr11:119,197,923...119,236,205
Ensembl chr11:119,198,594...119,236,201 		JBrowse link
G Casp8 caspase 8 IAGP MGI PMID:21135236 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Cdsn corneodesmosin IAGP MGI PMID:18436651 PMID:19596793 NCBI chr17:35,854,044...35,867,811
Ensembl chr17:35,863,025...35,868,077 		JBrowse link
G Cpa3 carboxypeptidase A3, mast cell IAGP MGI PMID:25843682 NCBI chr 3:20,269,780...20,296,373
Ensembl chr 3:20,269,784...20,296,345 		JBrowse link
G Ctsl cathepsin L IAGP MGI PMID:10199917 PMID:11023992 PMID:12163394 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Dsg4 desmoglein 4 IAGP MGI PMID:8752833 PMID:10839719 NCBI chr18:20,569,234...20,606,191
Ensembl chr18:20,569,232...20,604,878 		JBrowse link
G Dsp desmoplakin IAGP MGI PMID:25659760 NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 IAGP MGI PMID:9651581 PMID:16904611 PMID:17020410 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 IAGP MGI PMID:19114557 NCBI chr18:32,373,357...32,403,206
Ensembl chr18:32,373,353...32,403,204 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 IAGP MGI PMID:20703245 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 IAGP MGI PMID:20308431 PMID:25843682 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IAGP MGI PMID:20308431 PMID:22585574 PMID:25843682 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Flg filaggrin IAGP MGI PMID:11121144 PMID:19349982 PMID:23844115 PMID:24084074 NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993 		JBrowse link
G Gsdma3 gasdermin A3 IAGP MGI PMID:9434940 NCBI chr11:98,517,175...98,529,627
Ensembl chr11:98,517,186...98,529,052 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:32343482 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hr lysine demethylase and nuclear receptor corepressor IAGP MGI PMID:16455232 NCBI chr14:70,789,644...70,810,988
Ensembl chr14:70,789,652...70,810,988 		JBrowse link
G Il22 interleukin 22 IAGP MGI PMID:17187052 NCBI chr10:118,040,456...118,045,952
Ensembl chr10:118,040,847...118,045,952 		JBrowse link
G Il36rn interleukin 36 receptor antagonist IAGP MGI PMID:23064362 NCBI chr 2:24,166,966...24,172,444
Ensembl chr 2:24,166,966...24,173,438 		JBrowse link
G Ilk integrin linked kinase IAGP MGI PMID:18234842 NCBI chr 7:105,385,797...105,392,132
Ensembl chr 7:105,385,799...105,392,132 		JBrowse link
G Itgb2 integrin beta 2 IAGP MGI PMID:12819024 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Krt1 keratin 1 IAGP MGI PMID:16528356 NCBI chr15:101,753,861...101,759,221
Ensembl chr15:101,753,861...101,759,229 		JBrowse link
G Krt10 keratin 10 IAGP MGI PMID:8603923 NCBI chr11:99,276,080...99,288,631
Ensembl chr11:99,276,080...99,280,190 		JBrowse link
G Krt14 keratin 14 IAGP MGI PMID:29113991 NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374 		JBrowse link
G Krt2 keratin 2 IAGP MGI PMID:24751727 NCBI chr15:101,719,124...101,727,391
Ensembl chr15:101,719,124...101,726,604 		JBrowse link
G Krt9 keratin 9 IAGP MGI PMID:23962810 NCBI chr11:100,077,607...100,084,072
Ensembl chr11:100,077,607...100,084,072 		JBrowse link
G Lamc2 laminin, gamma 2 IAGP MGI PMID:20336083 NCBI chr 1:152,998,502...153,062,193
Ensembl chr 1:152,998,502...153,062,193 		JBrowse link
G Mpzl3 myelin protein zero-like 3 IAGP MGI PMID:24531688 NCBI chr 9:44,966,479...44,988,735
Ensembl chr 9:44,966,484...44,988,734 		JBrowse link
G Mta2 metastasis-associated gene family, member 2 IAGP MGI PMID:18353770 NCBI chr19:8,919,239...8,929,659
Ensembl chr19:8,919,239...8,929,667 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:8628301 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta IAGP MGI PMID:15491998 PMID:18441309 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A IAGP MGI PMID:9207103 NCBI chr  X:163,202,814...163,216,912
Ensembl chr  X:163,202,783...163,216,912 		JBrowse link
G Pkp3 plakophilin 3 IAGP MGI PMID:18079750 NCBI chr 7:140,658,202...140,670,424
Ensembl chr 7:140,658,131...140,670,423 		JBrowse link
G Pnpla1 patatin-like phospholipase domain containing 1 IAGP MGI PMID:27751867 PMID:28369476 NCBI chr17:29,077,262...29,109,282
Ensembl chr17:29,077,385...29,109,283 		JBrowse link
G Pstpip2 proline-serine-threonine phosphatase-interacting protein 2 IAGP MGI PMID:16397132 NCBI chr18:77,882,250...77,971,462
Ensembl chr18:77,877,614...77,970,579 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:18757421 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B IAGP MGI PMID:10940923 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363 		JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 IAGP MGI PMID:10854228 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318 		JBrowse link
G Sharpin SHANK-associated RH domain interacting protein IAGP MGI PMID:8774148 NCBI chr15:76,231,240...76,235,310
Ensembl chr15:76,231,240...76,235,311 		JBrowse link
G Snap29 synaptosomal-associated protein 29 IAGP MGI PMID:26747696 NCBI chr16:17,223,864...17,248,690
Ensembl chr16:17,223,850...17,248,691 		JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 IAGP MGI PMID:15619623 PMID:20703245 NCBI chr18:44,092,612...44,155,554
Ensembl chr18:44,096,302...44,155,568 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 IAGP MGI PMID:23633022 NCBI chr12:87,351,832...87,435,129
Ensembl chr12:87,351,832...87,435,129 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:14638864 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:10469645 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:18441309 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Supv3l1 suppressor of var1, 3-like 1 (S. cerevisiae) IAGP MGI PMID:19145458 NCBI chr10:62,265,000...62,287,294
Ensembl chr10:62,264,988...62,285,517 		JBrowse link
G Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 IAGP MGI PMID:27892606 NCBI chr 4:58,042,796...58,206,596
Ensembl chr 4:58,042,442...58,206,859 		JBrowse link
G Tmem79 transmembrane protein 79 IAGP MGI PMID:24060273 PMID:24084074 NCBI chr 3:88,236,351...88,241,761
Ensembl chr 3:88,235,962...88,243,455 		JBrowse link
G Trp63 transformation related protein 63 IAGP MGI PMID:16107615 NCBI chr16:25,502,513...25,710,842
Ensembl chr16:25,502,513...25,710,852 		JBrowse link
G Ttc7 tetratricopeptide repeat domain 7 IAGP MGI PMID:16093647 NCBI chr17:87,590,328...87,689,197
Ensembl chr17:87,590,314...87,689,197 		JBrowse link
G Tuft1 tuftelin 1 IAGP MGI PMID:37716648 NCBI chr 3:94,520,060...94,566,179
Ensembl chr 3:94,520,064...94,566,179 		JBrowse link
G Uros uroporphyrinogen III synthase IAGP MGI PMID:16532394 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A IAGP MGI PMID:19114557 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    integument phenotype 2836
      abnormal skin morphology 1657
        abnormal epidermal layer morphology 420
          abnormal epidermis stratum spinosum morphology 88
            epidermis stratum spinosum hyperplasia 57
              acanthosis 55
paths to the root