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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:abnormal corneocyte envelope morphology
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Accession:MP:0009594 term browser browse the term
Definition:any structural anomaly of the electron-dense layer of highly transglutaminase cross-linked protein that is deposited on the inner surface of the plasma membrane of corneocytes in the outermost layers of the epidermis; a monomolecular layer of ceramides is covalently attached to the outer surface of the CE to form a hydrophobic lipid envelope that covers each corneocyte and provides continuity with the lipid matrix
Synonyms:exact_synonym: abnormal cornified envelope morphology;   abnormal subplasmalemmal dense zone

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  mammalian phenotype 5402
    integument phenotype 171
      abnormal skin morphology 16
        abnormal epidermal layer morphology 2
          abnormal epidermis stratum corneum morphology 2
            abnormal corneocyte morphology 0
              abnormal corneocyte envelope morphology 0
                enlarged corneocyte envelope 0
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