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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal cumulus expansion
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Accession:MP:0009373 term browser browse the term
Definition:anomaly in the ability of the cumulus cells to synthesize and accumulate hyaluronan into an extracellular matrix (ECM), which provides an essential microenvironment for oocyte fertilization; this expanded ECM binds the oocyte and the cumulus cells together, protects the oocyte from the proteolytic and mechanical stresses during extrusion, and allows sperm binding, penetration, and fertilization
Synonyms:exact_synonym: abnormal ovarian cumulus expansion;   abnormal ovarian cumulus growth



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5400
    reproductive system phenotype 129
      abnormal reproductive system morphology 97
        abnormal sex gland morphology 67
          abnormal female reproductive gland morphology 24
            abnormal ovary morphology 24
              abnormal ovarian follicle morphology 5
                abnormal ovarian folliculogenesis 5
                  abnormal cumulus expansion 0
                    absent cumulus expansion 0
                    decreased cumulus expansion 0
                    increased cumulus expansion 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5400
    reproductive system phenotype 129
      abnormal reproductive system morphology 97
        abnormal female reproductive system morphology 30
          abnormal female genitalia morphology 27
            abnormal internal female genitalia morphology 27
              abnormal ovary morphology 24
                abnormal ovarian follicle morphology 5
                  abnormal ovarian folliculogenesis 5
                    abnormal cumulus expansion 0
                      absent cumulus expansion 0
                      decreased cumulus expansion 0
                      increased cumulus expansion 0
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