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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal cumulus expansion
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Accession:MP:0009373 term browser browse the term
Definition:anomaly in the ability of the cumulus cells to synthesize and accumulate hyaluronan into an extracellular matrix (ECM), which provides an essential microenvironment for oocyte fertilization; this expanded ECM binds the oocyte and the cumulus cells together, protects the oocyte from the proteolytic and mechanical stresses during extrusion, and allows sperm binding, penetration, and fertilization
Synonyms:exact_synonym: abnormal ovarian cumulus expansion;   abnormal ovarian cumulus growth



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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    reproductive system phenotype 0
      abnormal reproductive system morphology 0
        abnormal sex gland morphology 0
          abnormal female reproductive gland morphology 0
            abnormal ovary morphology 0
              abnormal ovarian follicle morphology 0
                abnormal ovarian folliculogenesis 0
                  abnormal cumulus expansion 0
                    absent cumulus expansion 0
                    decreased cumulus expansion 0
                    increased cumulus expansion 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    reproductive system phenotype 0
      abnormal reproductive system morphology 0
        abnormal female reproductive system morphology 0
          abnormal female genitalia morphology 0
            abnormal internal female genitalia morphology 0
              abnormal ovary morphology 0
                abnormal ovarian follicle morphology 0
                  abnormal ovarian folliculogenesis 0
                    abnormal cumulus expansion 0
                      absent cumulus expansion 0
                      decreased cumulus expansion 0
                      increased cumulus expansion 0
paths to the root