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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased large intestine adenocarcinoma incidence
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Accession:MP:0009310 term browser browse the term
Definition:higher than normal incidence of a malignant neoplasm of epithelial cells in the large intestine
Synonyms:related_synonym: large intestinal adenocarcinoma;   large intestine adenocarcinoma


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increased large intestine adenocarcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:20176656 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:8770874 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 IAGP MGI PMID:12208849 NCBI chr 7:27,004,566...27,039,142
Ensembl chr 7:27,004,561...27,037,117 		JBrowse link
G Mcc mutated in colorectal cancers IAGP MGI PMID:30831321 NCBI chr18:44,558,127...44,945,573
Ensembl chr18:44,558,127...44,945,249 		JBrowse link
G Rnf20 ring finger protein 20 IAGP MGI PMID:26854224 NCBI chr 4:49,632,005...49,656,887
Ensembl chr 4:49,632,006...49,656,887 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:19022904 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
increased anal adenocarcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:19022904 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
increased colon adenocarcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:21251616 PMID:25053805 PMID:26216032 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Ccdc80 coiled-coil domain containing 80 IAGP MGI PMID:25053805 NCBI chr16:44,913,770...44,948,287
Ensembl chr16:44,913,765...44,948,440 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IAGP MGI PMID:22201685 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413 		JBrowse link
G H2ax H2A.X variant histone IAGP MGI PMID:12914700 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:17617560 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IAGP MGI PMID:20133615 NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:22201685 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Pole polymerase (DNA directed), epsilon IAGP MGI PMID:19805137 NCBI chr 5:110,434,185...110,485,319
Ensembl chr 5:110,434,172...110,485,340 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:16488991 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Rab25 RAB25, member RAS oncogene family IAGP MGI PMID:20197623 NCBI chr 3:88,449,335...88,455,586
Ensembl chr 3:88,449,336...88,455,607 		JBrowse link
G Rnf20 ring finger protein 20 IAGP MGI PMID:26854224 NCBI chr 4:49,632,005...49,656,887
Ensembl chr 4:49,632,006...49,656,887 		JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:20197623 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Spata18 spermatogenesis associated 18 IAGP MGI PMID:26216032 NCBI chr 5:73,808,723...73,836,927
Ensembl chr 5:73,808,722...73,836,855 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:19022904 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tle5 TLE family member 5, transcriptional modulator IAGP MGI PMID:21251616 NCBI chr10:81,395,278...81,402,205
Ensembl chr10:81,395,322...81,402,196 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:12914700 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
increased rectum adenocarcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase IAGP MGI PMID:23878276 NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:19022904 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    digestive/alimentary phenotype 1925
      abnormal digestive system morphology 1580
        abnormal intestine morphology 749
          increased intestinal adenocarcinoma incidence 50
            increased large intestine adenocarcinoma incidence 19
              increased anal adenocarcinoma incidence 1
              increased cecum adenocarcinoma incidence 0
              increased colon adenocarcinoma incidence 16
              increased rectum adenocarcinoma incidence 2
Path 2
Term Annotations click to browse term
  mammalian phenotype 17065
    neoplasm 1367
      abnormal tumor susceptibility 1223
        abnormal tumor incidence 1202
          abnormal classified tumor incidence 754
            increased classified tumor incidence 737
              increased malignant tumor incidence 443
                increased carcinoma incidence 345
                  increased adenocarcinoma incidence 199
                    increased intestinal adenocarcinoma incidence 50
                      increased large intestine adenocarcinoma incidence 19
                        increased anal adenocarcinoma incidence 1
                        increased cecum adenocarcinoma incidence 0
                        increased colon adenocarcinoma incidence 16
                        increased rectum adenocarcinoma incidence 2
paths to the root