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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal pancreatic islet number
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Accession:MP:0009166 term browser browse the term
Definition:anomaly in the number of the clusters of hormone-producing cells that are scattered throughout the pancreas
Synonyms:exact_synonym: abnormal islands of Langerhans number;   abnormal islet cell number;   abnormal islet of Langerhans number



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absent pancreatic islets term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cys1 cystin 1 IAGP MGI PMID:4032601 PMID:11004214 NCBI chr12:24,715,832...24,731,794
Ensembl chr12:24,715,832...24,731,812
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22964416 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,044,389...113,054,294
JBrowse link
G Neurod1 neurogenic differentiation 1 IAGP MGI PMID:9308961 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095
JBrowse link
G Neurog3 neurogenin 3 IAGP MGI PMID:10677506 NCBI chr10:61,968,869...61,970,542
Ensembl chr10:61,968,869...61,970,542
JBrowse link
G Onecut1 one cut domain, family member 1 IAGP MGI PMID:19766716 NCBI chr 9:74,769,203...74,796,930
Ensembl chr 9:74,769,203...74,799,063
JBrowse link
G Pbx1 pre B cell leukemia homeobox 1 IAGP MGI PMID:11912494 NCBI chr 1:167,946,933...168,259,898
Ensembl chr 1:167,946,933...168,259,839
JBrowse link
decreased pancreatic islet number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IAGP MGI PMID:26432886 NCBI chr11:117,716,329...117,730,734
Ensembl chr11:117,716,750...117,730,734
JBrowse link
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:26411367 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like IAGP MGI PMID:20562852 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
JBrowse link
G Bglap bone gamma carboxyglutamate protein IAGP MGI PMID:17693256 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bglap2 bone gamma-carboxyglutamate protein 2 IAGP MGI PMID:17693256 NCBI chr 3:88,285,043...88,286,008
Ensembl chr 3:88,285,043...88,286,006
JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit IAGP MGI PMID:11581302 NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412
JBrowse link
G E2f1 E2F transcription factor 1 IAGP MGI PMID:15124020 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19187772 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,044,389...113,054,294
JBrowse link
G Hnf1b HNF1 homeobox B IAGP MGI PMID:33527355 NCBI chr11:83,741,035...83,796,743
Ensembl chr11:83,740,889...83,796,645
JBrowse link
G Icos inducible T cell co-stimulator IAGP MGI PMID:18292537 NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor IAGP MGI PMID:24726366 NCBI chr 9:106,765,952...106,769,137
Ensembl chr 9:106,715,511...106,769,178
JBrowse link
G Mir26a-1 microRNA 26a-1 IAGP MGI PMID:32092075 NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953
JBrowse link
G Mir26a-2 microRNA 26a-2 IAGP MGI PMID:32092075 NCBI chr10:126,831,399...126,831,482
Ensembl chr10:126,831,399...126,831,482
JBrowse link
G Ncoa5 nuclear receptor coactivator 5 IAGP MGI PMID:24332041 NCBI chr 2:164,842,273...164,876,794
Ensembl chr 2:164,842,277...164,876,787
JBrowse link
G Notch1 notch 1 IAGP MGI PMID:18635610 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
JBrowse link
G Notch2 notch 2 IAGP MGI PMID:18635610 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IAGP MGI PMID:12697734 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658
JBrowse link
G Pitpna phosphatidylinositol transfer protein, alpha IAGP MGI PMID:12788952 NCBI chr11:75,478,889...75,519,630
Ensembl chr11:75,478,923...75,519,630
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting IAGP MGI PMID:9326937 PMID:11689485 NCBI chr17:24,767,657...24,815,488
Ensembl chr17:24,768,808...24,815,482
JBrowse link
G Ptf1a pancreas specific transcription factor, 1a IAGP MGI PMID:18635610 NCBI chr 2:19,450,474...19,452,312
Ensembl chr 2:19,450,474...19,452,312
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IAGP MGI PMID:18635610 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704
JBrowse link
G Rnf146 ring finger protein 146 IAGP MGI PMID:28581440 NCBI chr10:29,220,172...29,238,438
Ensembl chr10:29,220,172...29,238,438
JBrowse link
G Sec23b SEC23 homolog B, COPII coat complex component IAGP MGI PMID:22745161 NCBI chr 2:144,398,149...144,432,673
Ensembl chr 2:144,398,149...144,432,669
JBrowse link
G Sertad1 SERTA domain containing 1 IAGP MGI PMID:20090907 NCBI chr 7:27,186,378...27,189,739
Ensembl chr 7:27,186,335...27,189,741
JBrowse link
G Tfb2m transcription factor B2, mitochondrial IAGP MGI PMID:28702322 NCBI chr 1:179,355,617...179,373,870
Ensembl chr 1:179,355,620...179,373,832
JBrowse link
G Tk1 thymidine kinase 1 IAGP MGI PMID:12559842 NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918
JBrowse link
increased pancreatic islet number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 thymoma viral proto-oncogene 2 IAGP MGI PMID:11387480 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
JBrowse link
G Bad BCL2-associated agonist of cell death IAGP MGI PMID:18223655 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Brd2 bromodomain containing 2 IAGP MGI PMID:19883376 NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608
JBrowse link
G Cpe carboxypeptidase E IEA MGI NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088
JBrowse link
G Ctf1 cardiotrophin 1 IAGP MGI PMID:21803294 NCBI chr 7:127,311,848...127,317,360
Ensembl chr 7:127,311,908...127,317,364
JBrowse link
G Gcg glucagon IAGP MGI PMID:19819987 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994
JBrowse link
G Gdf11 growth differentiation factor 11 IAGP MGI PMID:15548585 NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:24114270 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,044,389...113,054,294
JBrowse link
G Lep leptin IAGP MGI PMID:17465682 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Pax2 paired box 2 IAGP MGI PMID:15012626 NCBI chr19:44,735,040...44,826,708
Ensembl chr19:44,744,484...44,826,310
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:16537919 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IAGP MGI PMID:17693256 NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332
JBrowse link
G Selenot selenoprotein T IAGP MGI PMID:23913443 NCBI chr 3:58,484,057...58,500,965
Ensembl chr 3:58,484,057...58,500,554
JBrowse link
G Tlr3 toll-like receptor 3 IAGP MGI PMID:19357791 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 15939
    endocrine/exocrine gland phenotype 3124
      abnormal gland morphology 2899
        abnormal endocrine gland morphology 1226
          abnormal endocrine pancreas morphology 270
            abnormal pancreatic islet morphology 269
              abnormal pancreatic islet number 44
                decreased pancreatic islet number + 31
                increased pancreatic islet number 14
paths to the root