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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal pancreatic islet number
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Accession:MP:0009166 term browser browse the term
Definition:anomaly in the number of the clusters of hormone-producing cells that are scattered throughout the pancreas
Synonyms:exact_synonym: abnormal islands of Langerhans number;   abnormal islet cell number;   abnormal islet of Langerhans number


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decreased pancreatic islet number term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wfs1 wolframin ER transmembrane glycoprotein onset IMP RGD PMID:28860598 RGD:149735331 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
G Wfs1em1Ptsn wolframin ER transmembrane glycoprotein; ZFN induced mutant 1 onset IMP RGD PMID:28860598 RGD:149735331
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  mammalian phenotype 5419
    endocrine/exocrine gland phenotype 394
      abnormal gland morphology 333
        abnormal endocrine gland morphology 143
          abnormal endocrine pancreas morphology 24
            abnormal pancreatic islet morphology 24
              abnormal pancreatic islet number 4
                decreased pancreatic islet number + 4
                increased pancreatic islet number 0
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