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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal pancreatic acinar cell morphology
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Accession:MP:0009146 term browser browse the term
Definition:any structural anomaly of the secretory cells of the exocrine pancreas that produce fluid containing digestive enzymes
Synonyms:broad_synonym: abnormal pancreatic exocrine cell morphology


show annotations for term's descendants           Sort by:
abnormal pancreatic acinar cell morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 IAGP MGI PMID:17727724 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 IAGP MGI PMID:11696558 PMID:12829745 PMID:22510200 NCBI chr 5:144,127,104...144,131,259
Ensembl chr 5:144,127,104...144,131,259 		JBrowse link
G Braf Braf transforming gene IAGP MGI PMID:21383153 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397 		JBrowse link
G Ccpg1 cell cycle progression 1 IAGP MGI PMID:29290589 NCBI chr 9:72,892,692...72,923,622
Ensembl chr 9:72,892,711...72,923,622 		JBrowse link
G Cpa1 carboxypeptidase A1, pancreatic IAGP MGI PMID:30045879 NCBI chr 6:30,639,217...30,645,360
Ensembl chr 6:30,639,217...30,645,362 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 IAGP MGI PMID:24336520 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 IAGP MGI PMID:11997520 PMID:17727724 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229 		JBrowse link
G Gcgr glucagon receptor IAGP MGI PMID:21853126 NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits IAGP MGI PMID:25107912 NCBI chr10:88,215,130...88,283,186
Ensembl chr10:88,214,994...88,283,191 		JBrowse link
G Ift88 intraflagellar transport 88 IAGP MGI PMID:15226261 NCBI chr14:57,661,519...57,755,393
Ensembl chr14:57,661,519...57,755,393 		JBrowse link
G Invs inversin IAGP MGI PMID:9771707 NCBI chr 4:48,279,707...48,431,956
Ensembl chr 4:48,279,760...48,431,954 		JBrowse link
G Isl1 ISL1 transcription factor, LIM/homeodomain IAGP MGI PMID:9000074 NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225 		JBrowse link
G Itpr2 inositol 1,4,5-triphosphate receptor 2 IAGP MGI PMID:16195467 NCBI chr 6:146,009,797...146,403,757
Ensembl chr 6:146,009,797...146,403,721 		JBrowse link
G Itpr3 inositol 1,4,5-triphosphate receptor 3 IAGP MGI PMID:16195467 NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:29670173 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lpo lactoperoxidase IAGP MGI PMID:34127712 NCBI chr11:87,697,254...87,716,750
Ensembl chr11:87,697,254...87,719,115 		JBrowse link
G Man2b1 mannosidase 2, alpha B1 IAGP MGI PMID:10400983 NCBI chr 8:85,809,941...85,824,215
Ensembl chr 8:85,809,899...85,824,911 		JBrowse link
G Men1 multiple endocrine neoplasia 1 IAGP MGI PMID:11158604 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Meox2 mesenchyme homeobox 2 IAGP MGI PMID:25574476 NCBI chr12:37,158,539...37,229,533
Ensembl chr12:37,158,539...37,229,533 		JBrowse link
G Neurod1 neurogenic differentiation 1 IAGP MGI PMID:9308961 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095 		JBrowse link
G Neurog3 neurogenin 3 IAGP MGI PMID:10677506 NCBI chr10:61,968,869...61,970,542
Ensembl chr10:61,968,869...61,970,542 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IAGP MGI PMID:8631275 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:16169464 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptf1a pancreas specific transcription factor, 1a IAGP MGI PMID:25803032 PMID:29670173 NCBI chr 2:19,450,474...19,452,312
Ensembl chr 2:19,450,474...19,452,312 		JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 IAGP MGI PMID:25574476 NCBI chr11:86,574,900...86,583,283
Ensembl chr11:86,574,811...86,583,283 		JBrowse link
G Pzp PZP, alpha-2-macroglobulin like IAGP MGI PMID:10487856 NCBI chr 6:128,460,530...128,503,683
Ensembl chr 6:128,460,530...128,503,683 		JBrowse link
G Sec23b SEC23 homolog B, COPII coat complex component IAGP MGI PMID:22745161 PMID:26494538 NCBI chr 2:144,398,165...144,432,673
Ensembl chr 2:144,398,149...144,432,669 		JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 IAGP MGI PMID:12740569 NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527 		JBrowse link
G Serpini2 serine (or cysteine) peptidase inhibitor, clade I, member 2 IAGP MGI PMID:16184191 NCBI chr 3:75,149,664...75,177,385
Ensembl chr 3:75,149,677...75,177,385 		JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 IAGP MGI PMID:25100063 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683 		JBrowse link
G Smad4 SMAD family member 4 IAGP MGI PMID:25803032 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 IAGP MGI PMID:16083722 NCBI chr18:43,861,134...43,870,302
Ensembl chr18:43,861,147...43,870,622 		JBrowse link
G Stk11 serine/threonine kinase 11 IAGP MGI PMID:18227155 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 IAGP MGI PMID:15363411 NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686 		JBrowse link
G Yipf6 Yip1 domain family, member 6 IAGP MGI PMID:22802641 NCBI chr  X:97,979,922...97,992,627
Ensembl chr  X:97,979,922...97,992,623 		JBrowse link
G Zfp800 zinc finger protein 800 IAGP MGI PMID:33653874 NCBI chr 6:28,210,543...28,398,010
Ensembl chr 6:28,239,926...28,398,004 		JBrowse link
abnormal pancreatic acinar cell zymogen granule morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp12 aquaporin 12 IAGP MGI PMID:19726746 NCBI chr 1:92,934,056...92,939,991
Ensembl chr 1:92,934,056...92,939,991 		JBrowse link
G Atf4 activating transcription factor 4 IAGP MGI PMID:17727724 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 IAGP MGI PMID:11696558 PMID:15003629 PMID:22510200 NCBI chr 5:144,127,104...144,131,259
Ensembl chr 5:144,127,104...144,131,259 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 IAGP MGI PMID:24336520 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits IAGP MGI PMID:17962477 NCBI chr10:88,215,130...88,283,186
Ensembl chr10:88,214,994...88,283,191 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19897935 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Ppt2 palmitoyl-protein thioesterase 2 IAGP MGI PMID:14528005 NCBI chr17:34,835,636...34,856,993
Ensembl chr17:34,835,636...34,847,484 		JBrowse link
G Sc5d sterol-C5-desaturase IAGP MGI PMID:12812989 NCBI chr 9:42,162,888...42,175,607
Ensembl chr 9:42,162,891...42,175,552 		JBrowse link
G Serpini2 serine (or cysteine) peptidase inhibitor, clade I, member 2 IAGP MGI PMID:16184191 NCBI chr 3:75,149,664...75,177,385
Ensembl chr 3:75,149,677...75,177,385 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 IAGP MGI PMID:19897935 NCBI chr12:87,351,832...87,435,129
Ensembl chr12:87,351,832...87,435,129 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 IAGP MGI PMID:18535671 NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686 		JBrowse link
absent pancreatic acinar cell zymogen granule term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhbdf1 rhomboid 5 homolog 1 IAGP MGI PMID:23969955 NCBI chr11:32,159,585...32,172,339
Ensembl chr11:32,159,585...32,172,300 		JBrowse link
G Sec23b SEC23 homolog B, COPII coat complex component IAGP MGI PMID:22745161 NCBI chr 2:144,398,165...144,432,673
Ensembl chr 2:144,398,149...144,432,669 		JBrowse link
decreased pancreatic acinar cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpa1 carboxypeptidase A1, pancreatic IAGP MGI PMID:30045879 NCBI chr 6:30,639,217...30,645,360
Ensembl chr 6:30,639,217...30,645,362 		JBrowse link
G Cxadr coxsackie virus and adenovirus receptor IAGP MGI PMID:21674029 NCBI chr16:78,098,114...78,156,673
Ensembl chr16:78,098,377...78,156,662 		JBrowse link
G Gdf11 growth differentiation factor 11 IAGP MGI PMID:15548585 NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587 		JBrowse link
G Hnf1b HNF1 homeobox B IAGP MGI PMID:33527355 NCBI chr11:83,741,035...83,796,743
Ensembl chr11:83,740,889...83,796,645 		JBrowse link
G Ift88 intraflagellar transport 88 IAGP MGI PMID:11773599 NCBI chr14:57,661,519...57,755,393
Ensembl chr14:57,661,519...57,755,393 		JBrowse link
G Invs inversin IAGP MGI PMID:9771707 NCBI chr 4:48,279,707...48,431,956
Ensembl chr 4:48,279,760...48,431,954 		JBrowse link
G Onecut1 one cut domain, family member 1 IAGP MGI PMID:19766716 NCBI chr 9:74,769,203...74,796,930
Ensembl chr 9:74,769,203...74,799,063 		JBrowse link
G Prss3b protease, serine 3B IAGP MGI PMID:30487519 NCBI chr 6:41,007,202...41,012,443
Ensembl chr 6:41,007,202...41,012,443 		JBrowse link
G Ptf1a pancreas specific transcription factor, 1a IAGP MGI PMID:18635610 NCBI chr 2:19,450,474...19,452,312
Ensembl chr 2:19,450,474...19,452,312 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IAGP MGI PMID:18635610 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
G Sec23b SEC23 homolog B, COPII coat complex component IAGP MGI PMID:22745161 NCBI chr 2:144,398,165...144,432,673
Ensembl chr 2:144,398,149...144,432,669 		JBrowse link
ectopic pancreatic acinar cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cys1 cystin 1 IAGP MGI PMID:4032601 NCBI chr12:24,715,832...24,731,794
Ensembl chr12:24,715,832...24,731,812 		JBrowse link
increased pancreatic acinar cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:17980593 PMID:22146645 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 IAGP MGI PMID:22146645 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614 		JBrowse link
G Prox1 prospero homeobox 1 IAGP MGI PMID:16122728 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:16169464 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IAGP MGI PMID:22146645 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
pancreatic acinar cell atrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 IAGP MGI PMID:19033539 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator IAGP MGI PMID:7505691 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Ift88 intraflagellar transport 88 IAGP MGI PMID:10804177 NCBI chr14:57,661,519...57,755,393
Ensembl chr14:57,661,519...57,755,393 		JBrowse link
G Slc39a5 solute carrier family 39 (metal ion transporter), member 5 IAGP MGI PMID:24303081 NCBI chr10:128,231,796...128,237,145
Ensembl chr10:128,231,800...128,237,098 		JBrowse link
pancreatic acinar cell zymogen granule accumulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator IAGP MGI PMID:10570187 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Itpr2 inositol 1,4,5-triphosphate receptor 2 IAGP MGI PMID:16195467 NCBI chr 6:146,009,797...146,403,757
Ensembl chr 6:146,009,797...146,403,721 		JBrowse link
G Itpr3 inositol 1,4,5-triphosphate receptor 3 IAGP MGI PMID:16195467 NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197 		JBrowse link
G Neurod1 neurogenic differentiation 1 IAGP MGI PMID:9308961 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095 		JBrowse link
G Neurog3 neurogenin 3 IAGP MGI PMID:10677506 NCBI chr10:61,968,869...61,970,542
Ensembl chr10:61,968,869...61,970,542 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) IAGP MGI PMID:15159548 NCBI chr11:75,721,818...75,858,440
Ensembl chr11:75,721,825...75,829,255 		JBrowse link
G Sytl1 synaptotagmin-like 1 IAGP MGI PMID:18477466 NCBI chr 4:132,980,401...132,990,398
Ensembl chr 4:132,980,401...132,990,424 		JBrowse link
G Tk1 thymidine kinase 1 IAGP MGI PMID:12559842 NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 IAGP MGI PMID:15363411 NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17088
    digestive/alimentary phenotype 1927
      abnormal digestive system morphology 1581
        abnormal exocrine pancreas morphology 88
          abnormal pancreatic acinus morphology 63
            abnormal pancreatic acinar cell morphology 57
              abnormal pancreatic acinar cell zymogen granule morphology + 21
              absent pancreatic acinar cells 0
              decreased pancreatic acinar cell number 11
              ectopic pancreatic acinar cells 1
              increased pancreatic acinar cell number 5
              multinucleated pancreatic acinar cells 0
              pancreatic acinar cell atrophy 4
Path 2
Term Annotations click to browse term
  mammalian phenotype 17088
    endocrine/exocrine gland phenotype 3474
      abnormal gland morphology 3234
        abnormal pancreas morphology 474
          abnormal exocrine pancreas morphology 88
            abnormal pancreatic acinus morphology 63
              abnormal pancreatic acinar cell morphology 57
                abnormal pancreatic acinar cell zymogen granule morphology + 21
                absent pancreatic acinar cells 0
                decreased pancreatic acinar cell number 11
                ectopic pancreatic acinar cells 1
                increased pancreatic acinar cell number 5
                multinucleated pancreatic acinar cells 0
                pancreatic acinar cell atrophy 4
paths to the root