MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: decreased pancreatic beta cell mass
Accession: MP:0009114
browse the term
Definition: reduced total physical bulk or volume of a pancreatic beta cell compared to the normal state
Synonyms: exact_synonym: reduced pancreatic beta cell mass
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Ago2
argonaute RISC catalytic subunit 2
IAGP
MGI
PMID:24361012
NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784
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Alx3
aristaless-like homeobox 3
IAGP
MGI
PMID:21104068
NCBI chr 3:107,502,347...107,513,191
Ensembl chr 3:107,502,347...107,513,092
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Apc
APC, WNT signaling pathway regulator
IAGP
MGI
PMID:26411367
NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
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Bglap
bone gamma carboxyglutamate protein
IAGP
MGI
PMID:17693256
NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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Bglap2
bone gamma-carboxyglutamate protein 2
IAGP
MGI
PMID:17693256
NCBI chr 3:88,285,043...88,286,008
Ensembl chr 3:88,285,043...88,286,006
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Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
IAGP
MGI
PMID:11581302
NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412
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Cd38
CD38 antigen
IAGP
MGI
PMID:17003338
NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717
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Cdk8
cyclin dependent kinase 8
IAGP
MGI
PMID:31509750
NCBI chr 5:146,167,432...146,239,684
Ensembl chr 5:146,168,040...146,239,684
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Col5a3
collagen, type V, alpha 3
IAGP
MGI
PMID:21293061
NCBI chr 9:20,681,353...20,726,363
Ensembl chr 9:20,681,346...20,726,363
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Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
IAGP
MGI
PMID:15793246
NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109
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Extl3
exostosin-like glycosyltransferase 3
IAGP
MGI
PMID:19336225
NCBI chr14:65,289,508...65,387,322
Ensembl chr14:65,289,509...65,387,304
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Foxm1
forkhead box M1
IAGP
MGI
PMID:16556734
NCBI chr 6:128,339,957...128,352,849
Ensembl chr 6:128,339,930...128,353,109
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Gadd45gip1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
IAGP
MGI
PMID:25660120
NCBI chr 8:85,558,911...85,562,111
Ensembl chr 8:85,558,151...85,562,111
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Gck
glucokinase
IAGP
MGI
PMID:19952346 PMID:22698525 PMID:33558985
NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
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Gdf11
growth differentiation factor 11
IAGP
MGI
PMID:15548585
NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587
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Ghr
growth hormone receptor
IAGP
MGI
PMID:15138153 PMID:21555853 PMID:31806625
NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
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Gnao1
guanine nucleotide binding protein, alpha O
IAGP
MGI
PMID:20622165
NCBI chr 8:94,536,781...94,696,016
Ensembl chr 8:94,536,594...94,696,016
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Gsk3b
glycogen synthase kinase 3 beta
IAGP
MGI
PMID:18288891
NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
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Gt(ROSA)26Sor
gene trap ROSA 26, Philippe Soriano
IAGP
MGI
PMID:21557308 PMID:24332968 PMID:32092075
NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
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Hnf1a
HNF1 homeobox A
IAGP
MGI
PMID:9593777
NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153
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Hprt1
hypoxanthine phosphoribosyltransferase 1
IAGP
MGI
PMID:20364121
NCBI chr X:52,076,955...52,110,537
Ensembl chr X:52,077,014...52,110,536
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Htr2b
5-hydroxytryptamine (serotonin) receptor 2B
IAGP
MGI
PMID:31806625
NCBI chr 1:86,025,268...86,043,960
Ensembl chr 1:86,026,748...86,039,692
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Ildr2
immunoglobulin-like domain containing receptor 2
IAGP
MGI
PMID:18654634
NCBI chr 1:166,081,630...166,144,405
Ensembl chr 1:166,081,708...166,144,392
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Ins2
insulin II
IAGP
MGI
PMID:19955657 PMID:32640216
NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
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Insr
insulin receptor
IAGP
MGI
PMID:15254588 PMID:15372107 PMID:17416680 PMID:18288891
NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
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Irs2
insulin receptor substrate 2
IAGP
MGI
PMID:9495343 PMID:11078455 PMID:15467830 PMID:18288891
NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
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Jazf1
JAZF zinc finger 1
IAGP
MGI
PMID:32640216
NCBI chr 6:52,745,050...53,045,613
Ensembl chr 6:52,745,782...53,045,616
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Kcnh6
potassium voltage-gated channel, subfamily H (eag-related), member 6
IAGP
MGI
PMID:30590050
NCBI chr11:105,898,871...105,926,421
Ensembl chr11:105,898,950...105,925,375
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Lep
leptin
IAGP
MGI
PMID:16280642 PMID:18654634 PMID:19289822 PMID:24361012
NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
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Manf
mesencephalic astrocyte-derived neurotrophic factor
IAGP
MGI
PMID:24726366
NCBI chr 9:106,765,952...106,769,137
Ensembl chr 9:106,715,511...106,769,178
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Met
met proto-oncogene
IAGP
MGI
PMID:22427375
NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
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Mir375
microRNA 375
IAGP
MGI
PMID:19289822
NCBI chr 1:74,939,817...74,939,880
Ensembl chr 1:74,939,817...74,939,880
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Myd88
myeloid differentiation primary response gene 88
IAGP
MGI
PMID:19357791
NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
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Pdx1
pancreatic and duodenal homeobox 1
IAGP
MGI
PMID:12697734 PMID:15372107 PMID:19487809
NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658
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Prlr
prolactin receptor
IAGP
MGI
PMID:11897695
NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266
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Pten
phosphatase and tensin homolog
IAGP
MGI
PMID:21266327
NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
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Pttg1
pituitary tumor-transforming gene 1
IAGP
MGI
PMID:12626748
NCBI chr11:43,311,071...43,318,290
Ensembl chr11:43,311,077...43,317,078
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Rictor
RPTOR independent companion of MTOR, complex 2
IAGP
MGI
PMID:21266327
NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882
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Rps6kb1
ribosomal protein S6 kinase, polypeptide 1
IAGP
MGI
PMID:11140689 PMID:18846252
NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
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Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
IAGP
MGI
PMID:35472723
NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504
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Sertad1
SERTA domain containing 1
IAGP
MGI
PMID:20090907
NCBI chr 7:27,186,378...27,189,741
Ensembl chr 7:27,186,335...27,189,741
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Sgpp2
sphingosine-1-phosphate phosphatase 2
IAGP
MGI
PMID:27059959
NCBI chr 1:78,286,186...78,396,926
Ensembl chr 1:78,286,982...78,396,926
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Sh2b1
SH2B adaptor protein 1
IAGP
MGI
PMID:24150605
NCBI chr 7:126,066,165...126,075,882
Ensembl chr 7:126,066,166...126,074,596
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Slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
IAGP
MGI
PMID:9354799
NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
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Sox9
SRY (sex determining region Y)-box 9
IAGP
MGI
PMID:18723011
NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
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Speer6-ps1
spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1
IAGP
MGI
PMID:15372107
NCBI chr13:3,199,475...3,239,678
Ensembl chr13:3,236,206...3,239,317 Ensembl chr13:3,236,206...3,239,317
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Stat5a
signal transducer and activator of transcription 5A
IAGP
MGI
PMID:31806625
NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
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Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
IAGP
MGI
PMID:22717537
NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086
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Tfb2m
transcription factor B2, mitochondrial
IAGP
MGI
PMID:28702322
NCBI chr 1:179,355,617...179,373,870
Ensembl chr 1:179,355,620...179,373,832
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Tlr3
toll-like receptor 3
IAGP
MGI
PMID:19357791
NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
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Tph1
tryptophan hydroxylase 1
IAGP
MGI
PMID:31806625
NCBI chr 7:46,294,065...46,321,961
Ensembl chr 7:46,294,065...46,321,961
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Uox
urate oxidase
IAGP
MGI
PMID:28729031
NCBI chr 3:146,302,904...146,337,238
Ensembl chr 3:146,276,181...146,338,060
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Wfs1
wolframin ER transmembrane glycoprotein
IAGP
MGI
PMID:16215705
NCBI chr 5:37,123,448...37,146,326
Ensembl chr 5:37,123,448...37,146,549
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