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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased neuron number
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Accession:MP:0008948 term browser browse the term
Definition:fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses
Synonyms:exact_synonym: reduced neuron number
 broad_synonym: Abnormal neuron morphology
 xref: HP:0012757


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decreased neuron number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klf5 KLF transcription factor 5 IMP in hippocampus RGD PMID:32272873 RGD:45073134 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
decreased motor neuron number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase IMP DNA:deletion:exon: RGD PMID:28007901 RGD:12879399 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atmem1Kyo ATM serine/threonine kinase; ZFN induced mutant 1, Kyo IMP RGD PMID:28007901 RGD:12879399
decreased Purkinje cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc9a6 solute carrier family 9 member A6 IMP RGD PMID:34928329 RGD:151664747 NCBI chr  X:134,430,677...134,486,747
Ensembl chr  X:134,420,756...134,485,375 		JBrowse link
G Slc9a6 em1Moro solute carrier family 9 member A6;CRISPR/Cas9 induced mutant1, Moro IMP RGD PMID:34928329 RGD:151664747
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5417
    nervous system phenotype 376
      abnormal nervous system morphology 214
        abnormal neuron morphology 70
          abnormal neuron number 14
            decreased neuron number 12
              decreased Cajal-Retzius cell number + 0
              decreased Purkinje cell number 3
              decreased cerebellar granule cell number + 0
              decreased cerebral cortex pyramidal cell number + 0
              decreased dopaminergic neuron number 1
              decreased hippocampus pyramidal cell number + 0
              decreased motor neuron number 5
              decreased sensory neuron number + 2
paths to the root