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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased physiological sensitivity to xenobiotic
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Accession:MP:0008874 term browser browse the term
Definition:increase in the dose or concentration of a compound foreign to living organisms required to induce a specific level of physiological response or decrease in the severity of physiological response to a given dose or concentration of a compound foreign to living organisms
Synonyms:exact_synonym: decreased physiological sensitivity to xenobiotics;   decreased susceptibility to xenobiotics;   increased resistance to xenobiotics


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decreased incidence of tumors by chemical induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Mamtr6 Mammary tumor resistance QTL 6 TAS RGD PMID:19052818 RGD:2302423 NCBI chr18:19,278,901...83,218,561 JBrowse link
Q Mamtr7 Mammary tumor resistance QTL 7 IDA RGD PMID:19052818 RGD:2302423 NCBI chr10:9,658,275...104,670,812 JBrowse link
Q Mamtr8 Mammary tumor resistance QTL 8 IDA RGD PMID:19052818 RGD:2302423 NCBI chr18:31,359,408...83,218,561 JBrowse link
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  mammalian phenotype 5372
    homeostasis/metabolism phenotype 1393
      abnormal physiological response to xenobiotic 27
        decreased physiological sensitivity to xenobiotic 14
          decreased bronchoconstrictive response 0
          decreased incidence of tumors by chemical induction 12
          decreased susceptibility to neuronal excitotoxicity + 1
          decreased susceptibility to xenobiotic induced hyperthermia 0
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