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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:increased physiological sensitivity to xenobiotic
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Accession:MP:0008873 term browser browse the term
Definition:decrease in the dose or concentration of a compound foreign to living organisms required to induce a specific level of physiological response or increase in the severity of physiological response to a given dose or concentration of a compound foreign to living organisms
Synonyms:exact_synonym: decreased resistance to xenobiotics;   increased physiological sensitivity to xenobiotics;   increased susceptibility to xenobiotics

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increased incidence of tumors by chemical induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SPRD/Ztm MODEL: induced IAGP compared to 7,12-dimethyltetraphene treated WKY/Ztm RGD PMID:16596452 RGD:1599317
S SS.BN-(D6Rat119-D6Arb3)/Mcwi induced IAGP compared to SS/JrHsdMcwi RGD PMID:20737482 RGD:4143380 NCBI chr 6:106,752,656...132,339,866 JBrowse link
S SS.LEW-(D10Mco84-D10Rat58)/Mco induced IAGP compared to SS/Jr RGD PMID:27073989 RGD:11353863 NCBI chr10:67,502,108...67,785,171 JBrowse link
S STOCK-Tp53tm1(EGFP-Pac)Qly/Rrrc p53 knockout rat IAGP RGD PMID:22791818 RGD:12792958 NCBI chr10:54,300,070...54,311,525 JBrowse link
S WF/NHsd induced IAGP compared to WF.WKY-(D5Wox7-D5Uwm37)/Uwm RGD PMID:12844486 RGD:631852

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