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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal physiological response to xenobiotic
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Accession:MP:0008872 term browser browse the term
Definition:any anomaly in the physiological or morphological changes induced by a compound foreign to living organisms such as changes in blood pressure, changes in hormone or protein levels or hypertrophy or hypotrophy of an organ
Synonyms:exact_synonym: abnormal physiological response to xenobiotics
 related_synonym: abnormal response to xenobiotics


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decreased susceptibility to neuronal excitotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha IMP RGD PMID:16837598 RGD:13506279 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
increased susceptibility to xenobiotic induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 IMP RGD PMID:27071940 RGD:12910550 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfe2l2em1Kyo nuclear factor, erythroid 2-like 2; zinc finger nuclease induced mutant 1, Kyoto University IMP RGD PMID:27071940 RGD:12910550
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  mammalian phenotype 5373
    homeostasis/metabolism phenotype 1397
      abnormal physiological response to xenobiotic 28
        abnormal xenobiotic induced morbidity/mortality + 10
        decreased physiological sensitivity to xenobiotic + 15
        increased physiological sensitivity to xenobiotic + 5
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