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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to endotoxin shock
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Accession:MP:0008735 term browser browse the term
Definition:more than the expected early reaction of the microcirculation to endotoxins such as LPS, characterized by movement of fluid and leukocytes from the blood into extravascular tissues and often resulting in death
Synonyms:exact_synonym: decreased resistance to endotoxic shock;   decreased resistance to endotoxin shock;   increased sensitivity to endotoxic shock;   increased sensitivity to endotoxin shock;   increased susceptibility to endotoxic shock
 narrow_synonym: increased response to LPS induced shock



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  mammalian phenotype 5400
    immune system phenotype 499
      abnormal immune system physiology 381
        abnormal inflammatory response 229
          abnormal acute inflammation 5
            increased acute inflammation 4
              increased susceptibility to endotoxin shock 0
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