decreased interleukin-2 secretion - Ontology Report

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	decreased interleukin-2 secretion	go back to main search page
Accession:	MP:0008688	browse the term
Definition:	reduction in the production or release of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes
Synonyms:	exact_synonym:	decreased IL-2 secretion; decreased IL2 secretion; decreased RU 49637 secretion; decreased Ro-23-6019 secretion; decreased Ro-236019 secretion; decreased T-cell growth factor secretion; decreased T-cell stimulating factor secretion; decreased TCGF secretion; decreased interleukin II secretion; decreased interleukine 2 secretion; decreased lymphocyte mitogenic factor secretion; decreased thymocyte stimulating factor secretion; reduced IL-2 secretion; reduced IL2 secretion; reduced RU 49637 secretion; reduced Ro-23-6019 secretion; reduced Ro-236019 secretion; reduced T-cell growth factor secretion; reduced T-cell stimulating factor secretion; reduced TCGF secretion; reduced interleukin II secretion; reduced interleukine 2 secretion; reduced lymphocyte mitogenic factor secretion; reduced thymocyte stimulating factor secretion

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Strains (3)

decreased interleukin-2 secretion

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SHRSP.SHR-(rs197197017 -rs198445122)/Utx

IAGP

compared to SHR/Utx T cells

RGD

in T cells compared to SHR/Utx, SHRSP.SHR-(rs106374972-rs106170276)/Utx

RGD

compared to SHR/Utx, SHRSP.SHR-(rs197197017-rs198445122)/Utx T cells

RGD

PMID:32075490

RGD:150429819

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5380
immune system phenotype	495
abnormal immune system physiology	380
abnormal immune serum protein physiology	89
abnormal cytokine secretion	24
abnormal interleukin secretion	17
abnormal interleukin-2 secretion	3
decreased interleukin-2 secretion	3

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MAMMALIAN PHENOTYPE - ANNOTATIONS