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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:decreased interleukin-2 secretion
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Accession:MP:0008688 term browser browse the term
Definition:reduction in the production or release of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes
Synonyms:exact_synonym: decreased IL-2 secretion;   decreased IL2 secretion;   decreased RU 49637 secretion;   decreased Ro-23-6019 secretion;   decreased Ro-236019 secretion;   decreased T-cell growth factor secretion;   decreased T-cell stimulating factor secretion;   decreased TCGF secretion;   decreased interleukin II secretion;   decreased interleukine 2 secretion;   decreased lymphocyte mitogenic factor secretion;   decreased thymocyte stimulating factor secretion;   reduced IL-2 secretion;   reduced IL2 secretion;   reduced RU 49637 secretion;   reduced Ro-23-6019 secretion;   reduced Ro-236019 secretion;   reduced T-cell growth factor secretion;   reduced T-cell stimulating factor secretion;   reduced TCGF secretion;   reduced interleukin II secretion;   reduced interleukine 2 secretion;   reduced lymphocyte mitogenic factor secretion;   reduced thymocyte stimulating factor secretion

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decreased interleukin-2 secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SHRSP.SHR-(rs197197017 -rs198445122)/Utx IAGP compared to SHR/Utx T cells RGD PMID:32300198 RGD:149735373
S SHRSP/A3 IAGP in T cells compared to SHR/Utx, SHRSP.SHR-(rs106374972-rs106170276)/Utx RGD PMID:32300198 RGD:149735373
S SHRSP/BbbUtx IAGP compared to SHR/Utx, SHRSP.SHR-(rs197197017-rs198445122)/Utx T cells RGD PMID:32075490 RGD:150429819

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  mammalian phenotype 5380
    immune system phenotype 495
      abnormal immune system physiology 380
        abnormal immune serum protein physiology 89
          abnormal cytokine secretion 24
            abnormal interleukin secretion 17
              abnormal interleukin-2 secretion 3
                decreased interleukin-2 secretion 3
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