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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating interleukin-1 beta level
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Accession:MP:0008641 term browser browse the term
Definition:increased in the amount in the blood of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane
Synonyms:exact_synonym: increased circulating IL-1 beta level;   increased circulating IL-1b level;   increased circulating Il1b level;   increased circulating catabloin level
 narrow_synonym: Abnormal serum interleukin level
 xref: HP:0030782


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Path 1
Term Annotations click to browse term
  mammalian phenotype 8
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal immune serum protein physiology 0
          abnormal cytokine level 0
            abnormal interleukin level 0
              abnormal circulating interleukin level 0
                abnormal circulating interleukin-1 level 0
                  increased circulating interleukin-1 level 0
                    increased circulating interleukin-1 beta level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 8
    homeostasis/metabolism phenotype 0
      abnormal homeostasis 0
        abnormal protein level 0
          abnormal intercellular signaling peptide or protein level 0
            abnormal cytokine level 0
              abnormal interleukin level 0
                abnormal circulating interleukin level 0
                  increased circulating interleukin level 0
                    increased circulating interleukin-1 level 0
                      increased circulating interleukin-1 beta level 0
paths to the root