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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating interleukin-23 level
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Accession:MP:0008620 term browser browse the term
Definition:increase in the amount in the blood of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells
Comment:Interleukin-23 is comprised of a unique 19 kDa subunit (IL-23a) and 40 kDa subunit (IL-12b) that is shared with interleukin-12.
Synonyms:exact_synonym: increased circulating IL-23 level;   increased circulating IL23 level

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  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal immune serum protein physiology 0
          abnormal cytokine level 0
            abnormal interleukin level 0
              abnormal circulating interleukin level 0
                abnormal circulating interleukin-23 level 0
                  increased circulating interleukin-23 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    homeostasis/metabolism phenotype 0
      abnormal homeostasis 0
        abnormal protein level 0
          abnormal intercellular signaling peptide or protein level 0
            abnormal cytokine level 0
              abnormal circulating cytokine level 0
                abnormal circulating interleukin level 0
                  abnormal circulating interleukin-23 level 0
                    increased circulating interleukin-23 level 0
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