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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating interleukin-17 level
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Accession:MP:0008615 term browser browse the term
Definition:reduction in the amount in the blood of a proinflammatory cytokine produced primarily by T-cells or their precursors
Comment:Several subtypes of interleukin-17 have been identified, each of which is a product of a unique gene.
Synonyms:exact_synonym: decreased circulating IL-17 level;   decreased circulating IL17 level;   reduced circulating IL-17 level;   reduced circulating IL17 level
 narrow_synonym: decreased circulating CTLA-8 level;   decreased circulating CTLA8 level;   decreased circulating ML-1 level;   decreased circulating cytokine CX2 level;   decreased circulating cytotoxic T lymphocyte-associated antigen 8 level;   reduced circulating CTLA-8 level;   reduced circulating CTLA8 level;   reduced circulating ML-1 level;   reduced circulating cytokine CX2 level;   reduced circulating cytotoxic T lymphocyte-associated antigen 8 level



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decreased circulating interleukin-17 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4d C-type lectin domain family 4, member d IAGP MGI PMID:23602766 NCBI chr 6:123,239,066...123,252,227
Ensembl chr 6:123,239,070...123,252,224
JBrowse link
G Clec4e C-type lectin domain family 4, member e IAGP MGI PMID:23602766 NCBI chr 6:123,258,748...123,266,830
Ensembl chr 6:123,258,748...123,266,829
JBrowse link
G Clec7a C-type lectin domain family 7, member a IAGP MGI PMID:22038916 NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742
JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 IAGP MGI PMID:22590468 NCBI chr 2:25,134,825...25,145,458
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034
JBrowse link
G Zranb1 zinc finger, RAN-binding domain containing 1 IAGP MGI PMID:26808229 NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16979
    immune system phenotype 5728
      abnormal immune system physiology 3493
        abnormal immune serum protein physiology 1477
          abnormal cytokine level 605
            abnormal interleukin level 400
              abnormal circulating interleukin level 344
                abnormal circulating interleukin-17 level 34
                  decreased circulating interleukin-17 level 5
Path 2
Term Annotations click to browse term
  mammalian phenotype 16979
    homeostasis/metabolism phenotype 7878
      abnormal homeostasis 7023
        abnormal protein level 2353
          abnormal intercellular signaling peptide or protein level 620
            abnormal cytokine level 605
              abnormal circulating cytokine level 456
                abnormal circulating interleukin level 344
                  abnormal circulating interleukin-17 level 34
                    decreased circulating interleukin-17 level 5
paths to the root