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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal circulating interleukin-6 level
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Accession:MP:0008595 term browser browse the term
Definition:anomaly in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts
Synonyms:exact_synonym: abnormal circulating B cell stimulatory factor-2 level;   abnormal circulating B-cell differentiation factor level;   abnormal circulating B-cell differentiation factor-2 level;   abnormal circulating BSF-2 level;   abnormal circulating IFN-beta 2 level;   abnormal circulating IL-6 level;   abnormal circulating IL6 level;   abnormal circulating MGI-2 level;   abnormal circulating hepatocyte-stimulating factor level;   abnormal circulating hybridoma growth factor level;   abnormal circulating myeloid differentiation-inducing protein level;   abnormal circulating plasmacytoma growth factor level


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abnormal circulating interleukin-6 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 IAGP MGI PMID:23241891 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Mbl1 mannose-binding lectin (protein A) 1 IAGP MGI PMID:15148336 NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 IAGP MGI PMID:15148336 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) IAGP MGI PMID:12208866 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:21525133 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
decreased circulating interleukin-6 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IAGP MGI PMID:16403440 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:19347044 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Arid5a AT-rich interaction domain 5A IAGP MGI PMID:23676272 NCBI chr 1:36,346,814...36,363,117
Ensembl chr 1:36,346,814...36,363,110 		JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 IAGP MGI PMID:36217001 NCBI chr 9:59,295,837...59,395,469
Ensembl chr 9:59,295,541...59,393,901 		JBrowse link
G AW112010 expressed sequence AW112010 IAGP MGI PMID:30542152 NCBI chr19:11,024,976...11,027,930
Ensembl chr19:11,021,557...11,033,245 		JBrowse link
G Bbs12 Bardet-Biedl syndrome 12 IAGP MGI PMID:22958920 NCBI chr 3:37,366,695...37,383,334
Ensembl chr 3:37,366,703...37,375,602 		JBrowse link
G C3 complement component 3 IAGP MGI PMID:19620784 PMID:20709903 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C3ar1 complement component 3a receptor 1 IAGP MGI PMID:20709903 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120 		JBrowse link
G C5ar1 complement component 5a receptor 1 IAGP MGI PMID:20709903 NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465 		JBrowse link
G Casp1 caspase 1 IAGP MGI PMID:7859282 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase IAGP MGI PMID:7859282 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783 		JBrowse link
G Cd14 CD14 antigen IAGP MGI PMID:8612135 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:18467694 PMID:23509369 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061 		JBrowse link
G Clic4 chloride intracellular channel 4 IAGP MGI PMID:21469130 NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125 		JBrowse link
G Ctsc cathepsin C IAGP MGI PMID:18292580 NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 IAGP MGI PMID:20643340 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IEA MGI NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288 		JBrowse link
G F3 coagulation factor III IAGP MGI PMID:15215187 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Foxn1 forkhead box N1 IAGP MGI PMID:9820556 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:17581588 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gba1 glucosylceramidase beta 1 IAGP MGI PMID:20962279 NCBI chr 3:89,110,235...89,119,944
Ensembl chr 3:89,110,235...89,116,273 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:24339869 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hectd3 HECT domain E3 ubiquitin protein ligase 3 IAGP MGI PMID:29920190 NCBI chr 4:116,852,491...116,862,474
Ensembl chr 4:116,852,514...116,862,474 		JBrowse link
G Hspb8 heat shock protein 8 IAGP MGI PMID:21747053 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923 		JBrowse link
G Ifi204 interferon activated gene 204 IAGP MGI PMID:29472103 NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509 		JBrowse link
G Ifi35 interferon-induced protein 35 IAGP MGI PMID:29038465 NCBI chr11:101,339,238...101,349,527
Ensembl chr11:101,339,233...101,349,524 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 IAGP MGI PMID:24014876 NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819 		JBrowse link
G Il18 interleukin 18 IAGP MGI PMID:18573894 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:9278338 PMID:9317135 PMID:11994477 PMID:19347044 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:17581588 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6st interleukin 6 signal transducer IAGP MGI PMID:21148800 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 IAGP MGI PMID:19224918 NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IAGP MGI PMID:11923871 PMID:17470642 NCBI chr15:94,441,495...94,466,198
Ensembl chr15:94,441,524...94,479,696 		JBrowse link
G Irf5 interferon regulatory factor 5 IAGP MGI PMID:15665823 NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870 		JBrowse link
G Klhdc10 kelch domain containing 10 IAGP MGI PMID:27631783 NCBI chr 6:30,401,516...30,455,178
Ensembl chr 6:30,401,867...30,455,178 		JBrowse link
G Lrrc19 leucine rich repeat containing 19 IAGP MGI PMID:25026888 NCBI chr 4:94,523,958...94,538,381
Ensembl chr 4:94,524,890...94,538,381 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:18423196 PMID:22573811 PMID:31189603 PMID:36217001 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Mavs mitochondrial antiviral signaling protein IAGP MGI PMID:16785313 PMID:18178804 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945 		JBrowse link
G Msmp microseminoprotein, prostate associated IAGP MGI PMID:31813573 NCBI chr 4:43,583,216...43,584,494
Ensembl chr 4:43,583,216...43,584,494 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:18656388 PMID:22586041 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta IAGP MGI PMID:20740013 NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937 		JBrowse link
G Nmi N-myc (and STAT) interactor IAGP MGI PMID:29038465 NCBI chr 2:51,838,517...51,863,241
Ensembl chr 2:51,838,499...51,863,506 		JBrowse link
G Nmu neuromedin U IAGP MGI PMID:19070594 NCBI chr 5:76,481,342...76,511,624
Ensembl chr 5:76,481,342...76,511,635 		JBrowse link
G Peli1 pellino 1 IAGP MGI PMID:19734906 NCBI chr11:21,041,283...21,100,327
Ensembl chr11:21,041,291...21,100,323 		JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 IAGP MGI PMID:15340057 NCBI chr17:32,631,433...32,643,157
Ensembl chr17:32,631,433...32,643,141 		JBrowse link
G Pilrb1 paired immunoglobin-like type 2 receptor beta 1 IAGP MGI PMID:20065029 NCBI chr 5:137,850,403...137,856,687
Ensembl chr 5:137,850,409...137,856,368 		JBrowse link
G Plekhf1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 IAGP MGI PMID:31189603 NCBI chr 7:37,920,078...37,927,418
Ensembl chr 7:37,916,396...37,927,440 		JBrowse link
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit IAGP MGI PMID:19892703 NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567 		JBrowse link
G Ptgs2os prostaglandin-endoperoxide synthase 2, opposite strand IAGP MGI PMID:35365562 NCBI chr 1:149,950,624...149,975,625
Ensembl chr 1:149,950,624...149,975,714 		JBrowse link
G Retnlb resistin like beta IAGP MGI PMID:27397737 NCBI chr16:48,637,219...48,639,255
Ensembl chr16:48,637,219...48,639,255 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 IAGP MGI PMID:15869599 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Sgms1 sphingomyelin synthase 1 IAGP MGI PMID:22580896 NCBI chr19:32,100,127...32,367,285
Ensembl chr19:32,100,127...32,367,114 		JBrowse link
G Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin IAGP MGI PMID:22851711 NCBI chr 2:130,911,140...130,928,697
Ensembl chr 2:130,911,140...130,928,685 		JBrowse link
G Slc15a4 solute carrier family 15, member 4 IAGP MGI PMID:21277849 NCBI chr 5:127,668,795...127,710,356
Ensembl chr 5:127,672,728...127,709,961 		JBrowse link
G Spp1 secreted phosphoprotein 1 IAGP MGI PMID:17823662 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:21148800 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 IAGP MGI PMID:21813776 NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 IAGP MGI PMID:23509369 NCBI chr10:7,781,412...7,832,039
Ensembl chr10:7,781,417...7,831,994 		JBrowse link
G Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 IAGP MGI PMID:23509369 NCBI chr  X:84,617,466...84,678,075
Ensembl chr  X:84,617,628...84,678,075 		JBrowse link
G Thbd thrombomodulin IAGP MGI PMID:22573811 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 IAGP MGI PMID:18178804 PMID:18423196 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786 		JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein IAGP MGI PMID:21148800 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587 		JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:18423196 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:9426403 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IAGP MGI PMID:18719121 PMID:20457915 PMID:23676465 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tollip toll interacting protein IAGP MGI PMID:16428431 NCBI chr 7:141,435,317...141,456,198
Ensembl chr 7:141,428,550...141,472,244 		JBrowse link
G Tradd TNFRSF1A-associated via death domain IAGP MGI PMID:18719121 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241 		JBrowse link
G Traf6 TNF receptor-associated factor 6 IAGP MGI PMID:18423196 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014 		JBrowse link
G Trim41 tripartite motif-containing 41 IAGP MGI PMID:33640899 NCBI chr11:48,697,230...48,709,026
Ensembl chr11:48,697,231...48,708,180 		JBrowse link
G Txndc2 thioredoxin domain containing 2 (spermatozoa) IEA MGI NCBI chr17:65,944,498...65,955,871
Ensembl chr17:65,944,502...65,949,163 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator IAGP MGI PMID:24778236 NCBI chr19:3,985,222...3,999,340
Ensembl chr19:3,985,186...3,999,340 		JBrowse link
G Usp20 ubiquitin specific peptidase 20 IAGP MGI PMID:30814308 NCBI chr 2:30,872,291...30,912,667
Ensembl chr 2:30,872,291...30,913,598 		JBrowse link
G Zcchc3 zinc finger, CCHC domain containing 3 IAGP MGI PMID:30135424 NCBI chr 2:152,253,875...152,256,711
Ensembl chr 2:152,253,875...152,256,947 		JBrowse link
G Zdhhc1 zinc finger, DHHC domain containing 1 IAGP MGI PMID:25299331 NCBI chr 8:106,199,055...106,223,694
Ensembl chr 8:106,199,055...106,223,534 		JBrowse link
G Zdhhc11 zinc finger, DHHC domain containing 11 IAGP MGI PMID:34490261 NCBI chr13:74,111,970...74,141,109
Ensembl chr13:74,111,970...74,141,109 		JBrowse link
increased circulating interleukin-6 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamdec1 ADAM-like, decysin 1 IAGP MGI PMID:27226416 NCBI chr14:68,800,829...68,819,535
Ensembl chr14:68,800,829...68,819,544 		JBrowse link
G Adar adenosine deaminase, RNA-specific IAGP MGI PMID:34332594 NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753 		JBrowse link
G Adora2b adenosine A2b receptor IAGP MGI PMID:16823489 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279 		JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:22185842 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Arrb2 arrestin, beta 2 IAGP MGI PMID:16378096 NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654 		JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase IAGP MGI PMID:24012418 NCBI chr 3:88,857,721...88,986,682
Ensembl chr 3:88,857,929...88,986,682 		JBrowse link
G Atg16l1 autophagy related 16 like 1 IAGP MGI PMID:23973919 NCBI chr 1:87,683,730...87,720,150
Ensembl chr 1:87,683,592...87,720,150 		JBrowse link
G Atg5 autophagy related 5 IAGP MGI PMID:27096368 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Atg7 autophagy related 7 IAGP MGI PMID:27096368 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Bag4 BCL2-associated athanogene 4 IAGP MGI PMID:12748303 NCBI chr 8:26,254,566...26,275,237
Ensembl chr 8:26,254,566...26,275,315 		JBrowse link
G Becn1 beclin 1, autophagy related IAGP MGI PMID:27096368 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G C1qtnf4 C1q and tumor necrosis factor related protein 4 IAGP MGI PMID:33080044 NCBI chr 2:90,713,132...90,720,870
Ensembl chr 2:90,716,204...90,720,869 		JBrowse link
G C4bp complement component 4 binding protein IAGP MGI PMID:28542817 NCBI chr 1:130,562,510...130,589,365
Ensembl chr 1:130,562,510...130,589,369 		JBrowse link
G Cav1 caveolin 1, caveolae protein IAGP MGI PMID:16982844 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:31086255 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061 		JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:15781582 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:23955076 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta IAGP MGI PMID:7744000 PMID:20047998 PMID:28476751 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Colgalt2 collagen beta(1-O)galactosyltransferase 2 IAGP MGI PMID:30355948 NCBI chr 1:152,275,485...152,386,942
Ensembl chr 1:152,275,581...152,386,446 		JBrowse link
G Crh corticotropin releasing hormone IAGP MGI PMID:11602623 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 IAGP MGI PMID:20042581 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 IAGP MGI PMID:20042581 NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388 		JBrowse link
G Ctsc cathepsin C IAGP MGI PMID:14966572 NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IAGP MGI PMID:8036519 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide IAGP MGI PMID:27096368 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IAGP MGI PMID:22185842 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Cyrib CYFIP related Rac1 interactor B IAGP MGI PMID:31285585 NCBI chr15:63,800,943...63,932,627
Ensembl chr15:63,800,946...63,932,327 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IAGP MGI PMID:16380512 PMID:16424221 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102 		JBrowse link
G Dusp11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) IAGP MGI PMID:32796023 NCBI chr 6:85,919,250...85,938,950
Ensembl chr 6:85,919,250...85,938,649 		JBrowse link
G Dusp22 dual specificity phosphatase 22 IAGP MGI PMID:24714587 NCBI chr13:30,844,042...30,895,215
Ensembl chr13:30,843,982...30,895,214 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IAGP MGI PMID:22201685 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413 		JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 IAGP MGI PMID:36656709 NCBI chr 4:134,083,684...134,099,893
Ensembl chr 4:134,083,683...134,111,161 		JBrowse link
G Fis1 fission, mitochondrial 1 IAGP MGI PMID:31526891 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088 		JBrowse link
G Flt3 FMS-like tyrosine kinase 3 IAGP MGI PMID:20457904 NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:16275384 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Ghr growth hormone receptor IAGP MGI PMID:23349524 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha IAGP MGI PMID:20357757 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IAGP MGI PMID:20357757 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23955076 PMID:24376268 PMID:24498102 PMID:29263322 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hmgb1 high mobility group box 1 IAGP MGI PMID:24361123 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Ifnar2 interferon (alpha and beta) receptor 2 IAGP MGI PMID:21148800 NCBI chr16:91,166,517...91,202,477
Ensembl chr16:91,169,671...91,202,477 		JBrowse link
G Ifng interferon gamma IAGP MGI PMID:9531602 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:21709234 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Ikbip IKBKB interacting protein IAGP MGI PMID:31826938 NCBI chr10:90,918,667...90,938,475
Ensembl chr10:90,918,802...90,938,469 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:18650318 PMID:19941312 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il10ra interleukin 10 receptor, alpha IAGP MGI PMID:19941312 NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447 		JBrowse link
G Il10rb interleukin 10 receptor, beta IAGP MGI PMID:18318596 NCBI chr16:91,203,166...91,222,718
Ensembl chr16:91,203,052...91,222,722 		JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:37315560 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Il1r2 interleukin 1 receptor, type II IAGP MGI PMID:38329807 NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IAGP MGI PMID:10749768 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il27ra interleukin 27 receptor, alpha IAGP MGI PMID:15004160 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218 		JBrowse link
G Il6ra interleukin 6 receptor, alpha IAGP MGI PMID:20816090 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Il6st interleukin 6 signal transducer IAGP MGI PMID:21148800 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Ing4 inhibitor of growth family, member 4 IAGP MGI PMID:20534538 NCBI chr 6:125,016,811...125,026,228
Ensembl chr 6:125,016,723...125,026,228 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IAGP MGI PMID:12161749 PMID:15831701 PMID:21421839 NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Irf1 interferon regulatory factor 1 IAGP MGI PMID:9379011 PMID:12807824 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Itgb2 integrin beta 2 IAGP MGI PMID:9653089 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Itln1 intelectin 1 (galactofuranose binding) IAGP MGI PMID:29619269 NCBI chr 1:171,345,691...171,362,893
Ensembl chr 1:171,345,690...171,362,862 		JBrowse link
G Junb jun B proto-oncogene IAGP MGI PMID:19918056 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 IAGP MGI PMID:22308309 NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879 		JBrowse link
G Ldlr low density lipoprotein receptor IAGP MGI PMID:18410513 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Lepr leptin receptor IAGP MGI PMID:16373670 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Lif leukemia inhibitory factor IAGP MGI PMID:15702085 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514 		JBrowse link
G Lrrc4c leucine rich repeat containing 4C IEA MGI NCBI chr 2:96,148,514...97,466,871
Ensembl chr 2:96,148,514...97,462,011 		JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated IAGP MGI PMID:29706547 NCBI chr 6:91,493,017...91,499,602
Ensembl chr 6:91,492,910...91,499,607 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:23940344 NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:19501000 PMID:21119595 PMID:22201685 PMID:27096368 PMID:28476751 More... NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Marchf2 membrane associated ring-CH-type finger 2 IAGP MGI PMID:32935379 NCBI chr17:33,904,666...33,937,651
Ensembl chr17:33,904,666...33,937,644 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 IAGP MGI PMID:26246171 NCBI chr19:37,184,939...37,201,856
Ensembl chr19:37,184,942...37,199,550 		JBrowse link
G Mavs mitochondrial antiviral signaling protein IAGP MGI PMID:20140199 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945 		JBrowse link
G Mc4r melanocortin 4 receptor IAGP MGI PMID:21906580 NCBI chr18:66,990,776...66,993,558
Ensembl chr18:66,990,775...66,993,577 		JBrowse link
G Mefv Mediterranean fever IAGP MGI PMID:21600797 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961 		JBrowse link
G Mep1a meprin 1 alpha IAGP MGI PMID:19262505 NCBI chr17:43,785,215...43,815,034
Ensembl chr17:43,785,215...43,813,703 		JBrowse link
G Mir122 microRNA 122 IAGP MGI PMID:22820288 PMID:22820290 NCBI chr18:65,381,932...65,381,997
Ensembl chr18:65,381,932...65,381,997 		JBrowse link
G Mir146 microRNA 146 IAGP MGI PMID:21555486 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G N4bp1 NEDD4 binding protein 1 IAGP MGI PMID:32971525 NCBI chr 8:87,567,764...87,612,489
Ensembl chr 8:87,534,788...87,611,886 		JBrowse link
G Nckap1l NCK associated protein 1 like IAGP MGI PMID:19015308 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 IAGP MGI PMID:17349961 NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,545...165,915,162 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 IAGP MGI PMID:18395094 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 IAGP MGI PMID:22863753 NCBI chr16:3,762,871...3,796,881
Ensembl chr16:3,762,871...3,794,496 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 IAGP MGI PMID:19501000 PMID:22558291 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Nlrx1 NLR family member X1 IAGP MGI PMID:21703540 NCBI chr 9:44,164,010...44,179,896
Ensembl chr 9:44,164,014...44,179,896 		JBrowse link
G Notch2 notch 2 IAGP MGI PMID:28856714 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677 		JBrowse link
G Otub1 OTU domain, ubiquitin aldehyde binding 1 IAGP MGI PMID:31086255 NCBI chr19:7,175,571...7,183,649
Ensembl chr19:7,175,567...7,183,681 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IAGP MGI PMID:22396549 NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980 		JBrowse link
G Pomc pro-opiomelanocortin-alpha IAGP MGI PMID:12458044 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha IAGP MGI PMID:17932564 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:15069016 PMID:23160464 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459 		JBrowse link
G Procr protein C receptor, endothelial IAGP MGI PMID:26045607 NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391 		JBrowse link
G Psmb10 proteasome (prosome, macropain) subunit, beta type 10 IAGP MGI PMID:29654304 NCBI chr 8:106,662,360...106,665,024
Ensembl chr 8:106,662,367...106,665,076 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IAGP MGI PMID:21575863 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IAGP MGI PMID:21435452 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Pycard PYD and CARD domain containing IAGP MGI PMID:29263322 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:23160464 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911 		JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:21600797 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Ramp1 receptor (calcitonin) activity modifying protein 1 IAGP MGI PMID:17923674 NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918 		JBrowse link
G Rdur RIG-I dependent antiviral response regulator RNA IAGP MGI PMID:34054851 NCBI chr16:55,520,102...55,577,639 JBrowse link
G Rhbdd3 rhomboid domain containing 3 IAGP MGI PMID:23610400 NCBI chr11:5,048,282...5,056,100
Ensembl chr11:5,048,926...5,056,093 		JBrowse link
G Rnf122 ring finger protein 122 IAGP MGI PMID:27506794 NCBI chr 8:31,601,855...31,623,346
Ensembl chr 8:31,601,848...31,621,510 		JBrowse link
G Rps6ka4 ribosomal protein S6 kinase, polypeptide 4 IAGP MGI PMID:18690222 NCBI chr19:6,806,573...6,819,513
Ensembl chr19:6,806,578...6,818,004 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase, polypeptide 5 IAGP MGI PMID:18690222 NCBI chr12:100,514,692...100,691,693
Ensembl chr12:100,514,698...100,693,242 		JBrowse link
G Rubcn RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein IAGP MGI PMID:27096368 NCBI chr16:32,642,072...32,698,121
Ensembl chr16:32,642,073...32,698,136 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 IAGP MGI PMID:16964311 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Sectm1a secreted and transmembrane 1A IAGP MGI PMID:32170929 NCBI chr11:120,958,221...120,988,023
Ensembl chr11:120,958,233...120,972,046 		JBrowse link
G Senp1 SUMO1/sentrin specific peptidase 1 IAGP MGI PMID:26596471 NCBI chr15:97,936,625...97,991,625
Ensembl chr15:97,936,625...97,991,625 		JBrowse link
G Sh3bp2 SH3-domain binding protein 2 IAGP MGI PMID:25705883 NCBI chr 5:34,683,128...34,720,983
Ensembl chr 5:34,683,182...34,720,985 		JBrowse link
G Siglece sialic acid binding Ig-like lectin E IAGP MGI PMID:28100677 NCBI chr 7:43,300,494...43,309,585
Ensembl chr 7:43,300,494...43,309,585 		JBrowse link
G Sirt3 sirtuin 3 IAGP MGI PMID:21856199 NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222 		JBrowse link
G Smg1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase IAGP MGI PMID:23277562 NCBI chr 7:117,730,531...117,843,026
Ensembl chr 7:117,730,531...117,842,893 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B IAGP MGI PMID:26095358 NCBI chr 4:132,460,277...132,484,558
Ensembl chr 4:132,460,277...132,484,563 		JBrowse link
G Snrk SNF related kinase IAGP MGI PMID:29298809 NCBI chr 9:121,946,332...121,998,768
Ensembl chr 9:121,946,332...121,998,768 		JBrowse link
G Snrnp40 small nuclear ribonucleoprotein 40 (U5) IAGP MGI PMID:31427773 NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819 		JBrowse link
G Sod1 superoxide dismutase 1, soluble IAGP MGI PMID:25036096 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:16964311 PMID:21575863 PMID:22820288 NCBI chr13:3,199,475...3,239,678
Ensembl chr13:3,236,206...3,239,317
Ensembl chr13:3,236,206...3,239,317 		JBrowse link
G Stk38 serine/threonine kinase 38 IAGP MGI PMID:25981615 NCBI chr17:29,189,854...29,226,979
Ensembl chr17:29,189,854...29,226,969 		JBrowse link
G Stx11 syntaxin 11 IAGP MGI PMID:23160464 NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042 		JBrowse link
G Tbc1d23 TBC1 domain family, member 23 IAGP MGI PMID:22312129 NCBI chr16:56,989,225...57,051,891
Ensembl chr16:56,989,225...57,051,867 		JBrowse link
G Tbk1 TANK-binding kinase 1 IAGP MGI PMID:20651301 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 IAGP MGI PMID:30254643 NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919 		JBrowse link
G Thbd thrombomodulin IAGP MGI PMID:11518727 PMID:11557684 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Timd4 T cell immunoglobulin and mucin domain containing 4 IAGP MGI PMID:27096368 NCBI chr11:46,701,613...46,735,160
Ensembl chr11:46,701,627...46,735,159 		JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:8982246 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:35477763 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IAGP MGI PMID:20530205 PMID:24498102 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 IAGP MGI PMID:25948814 NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240 		JBrowse link
G Tnfaip8l2 tumor necrosis factor, alpha-induced protein 8-like 2 IAGP MGI PMID:18455983 NCBI chr 3:95,046,832...95,051,581
Ensembl chr 3:95,046,832...95,049,671 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 IAGP MGI PMID:18849341 NCBI chr 5:121,509,788...121,524,543
Ensembl chr 5:121,509,788...121,523,695 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 IAGP MGI PMID:28559417 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
G Trim38 tripartite motif-containing 38 IAGP MGI PMID:26392463 NCBI chr13:23,962,483...23,975,721
Ensembl chr13:23,953,896...23,975,511 		JBrowse link
G Trim8 tripartite motif-containing 8 IAGP MGI PMID:28747347 NCBI chr19:46,490,087...46,504,894
Ensembl chr19:46,490,141...46,505,287 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:21411755 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G U90926 cDNA sequence U90926 IAGP MGI PMID:36705532 NCBI chr 5:92,357,754...92,363,211
Ensembl chr 5:92,357,752...92,363,267 		JBrowse link
G Ube2s ubiquitin-conjugating enzyme E2S IAGP MGI PMID:32814047 NCBI chr 7:4,811,013...4,815,339
Ensembl chr 7:4,797,545...4,815,589 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 IAGP MGI PMID:20693420 NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876 		JBrowse link
G Usp49 ubiquitin specific peptidase 49 IAGP MGI PMID:30943264 NCBI chr17:47,941,615...47,997,664
Ensembl chr17:47,941,615...47,997,663 		JBrowse link
G Wasl WASP like actin nucleation promoting factor IAGP MGI PMID:28779153 NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008 		JBrowse link
G Wwp2 WW domain containing E3 ubiquitin protein ligase 2 IAGP MGI PMID:23479606 NCBI chr 8:108,162,966...108,285,922
Ensembl chr 8:108,162,997...108,285,227 		JBrowse link
G Zg16 zymogen granule protein 16 IAGP MGI PMID:27849619 NCBI chr 7:126,649,328...126,651,847
Ensembl chr 7:126,649,328...126,686,500 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16962
    immune system phenotype 5703
      abnormal immune system physiology 3483
        abnormal immune serum protein physiology 1475
          abnormal cytokine level 605
            abnormal interleukin level 400
              abnormal circulating interleukin level 344
                abnormal circulating interleukin-6 level 208
                  decreased circulating interleukin-6 level 75
                  increased circulating interleukin-6 level 140
Path 2
Term Annotations click to browse term
  mammalian phenotype 16962
    homeostasis/metabolism phenotype 7866
      abnormal homeostasis 7015
        abnormal protein level 2351
          abnormal intercellular signaling peptide or protein level 620
            abnormal cytokine level 605
              abnormal circulating cytokine level 456
                abnormal circulating interleukin level 344
                  abnormal circulating interleukin-6 level 208
                    decreased circulating interleukin-6 level 75
                    increased circulating interleukin-6 level 140
paths to the root