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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating interleukin-1 level
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Accession:MP:0008592 term browser browse the term
Definition:reduction in the amount in the blood of a soluble factor produced by monocytes, macrophages and other cells, which activates T-lymphocytes and potentiates their response to mitogens or antigens
Synonyms:exact_synonym: decreased circulating IL-1 level;   decreased circulating T helper factor level;   decreased circulating epidermal cell derived thymocyte-activating factor level;   decreased circulating interleukin I level;   decreased circulating lymphocyte-activating factor level;   decreased circulating macrophage cell factor level;   reduced circulating IL-1 level;   reduced circulating T helper factor level;   reduced circulating epidermal cell derived thymocyte-activating factor level;   reduced circulating interleukin I level;   reduced circulating lymphocyte-activating factor level;   reduced circulating macrophage cell factor level



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decreased circulating interleukin-1 beta level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BN/Ka Brown Norway Katholiek (kininogen or kinin deficient) MODEL: induced IAGP compared to BN RGD PMID:15238617 PMID:15238617 RGD:1302825, RGD:1302825

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 519
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                abnormal circulating interleukin-1 level 2
                  decreased circulating interleukin-1 level 1
                    decreased circulating interleukin-1 alpha level 0
                    decreased circulating interleukin-1 beta level 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  abnormal circulating interleukin-1 level 2
                    decreased circulating interleukin-1 level 1
                      decreased circulating interleukin-1 alpha level 0
                      decreased circulating interleukin-1 beta level 1
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