Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating tumor necrosis factor level
go back to main search page
Accession:MP:0008554 term browser browse the term
Definition:reduction in the amount in the blood of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium
Synonyms:exact_synonym: decreased circulating TNF level;   decreased circulating TNFA level;   decreased circulating cachectin level;   decreased circulating tumor necrosis factor alpha level;   decreased circulating tumour necrosis factor alpha level;   decreased circulating tumour necrosis factor level;   reduced circulating TNF level;   reduced circulating TNFA level;   reduced circulating cachectin level;   reduced circulating tumor necrosis factor alpha level;   reduced circulating tumor necrosis factor level;   reduced circulating tumour necrosis factor alpha level;   reduced circulating tumour necrosis factor level



show annotations for term's descendants           Sort by:
 
decreased circulating tumor necrosis factor level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5364
    immune system phenotype 492
      abnormal immune system physiology 377
        abnormal immune serum protein physiology 87
          abnormal cytokine level 34
            abnormal tumor necrosis factor level 10
              abnormal circulating tumor necrosis factor level 7
                decreased circulating tumor necrosis factor level 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5364
    homeostasis/metabolism phenotype 1389
      abnormal homeostasis 1295
        abnormal protein level 128
          abnormal intercellular signaling peptide or protein level 35
            abnormal cytokine level 34
              abnormal circulating cytokine level 24
                abnormal circulating tumor necrosis factor level 7
                  decreased circulating tumor necrosis factor level 3
paths to the root