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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal circulating tumor necrosis factor level
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Accession:MP:0008552 term browser browse the term
Definition:anomaly in the amount in the blood of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium
Synonyms:exact_synonym: abnormal circulating TNFA level;   abnormal circulating cachectin level;   abnormal circulating tumor necrosis factor alpha level;   abnormal circulating tumour necrosis factor alpha level;   abnormal circulating tumour necrosis factor level
 related_synonym: abnormal circulating TNF level


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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal immune serum protein physiology 0
          abnormal cytokine level 0
            abnormal tumor necrosis factor level 0
              abnormal circulating tumor necrosis factor level 0
                decreased circulating tumor necrosis factor level 0
                increased circulating tumor necrosis factor level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    homeostasis/metabolism phenotype 0
      abnormal homeostasis 0
        abnormal protein level 0
          abnormal intercellular signaling peptide or protein level 0
            abnormal cytokine level 0
              abnormal circulating cytokine level 0
                abnormal circulating tumor necrosis factor level 0
                  decreased circulating tumor necrosis factor level 0
                  increased circulating tumor necrosis factor level 0
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