MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: increased spleen red pulp amount
Accession: MP:0008476
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Definition: increase in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation
Synonyms: exact_synonym: increased splenic red pulp
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Adam10
a disintegrin and metallopeptidase domain 10
IAGP
MGI
PMID:22042698
NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511
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Adam17
a disintegrin and metallopeptidase domain 17
IAGP
MGI
PMID:19201862
NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
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Akap12
A kinase anchor protein 12
IAGP
MGI
PMID:18593908
NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470
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Asl
argininosuccinate lyase
IAGP
MGI
PMID:22081021
NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088
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Bak1
BCL2-antagonist/killer 1
IAGP
MGI
PMID:11163212
NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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Bax
BCL2-associated X protein
IAGP
MGI
PMID:11163212
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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Bnip3l
BCL2/adenovirus E1B interacting protein 3-like
IAGP
MGI
PMID:17420462
NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326
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Cbl
Casitas B-lineage lymphoma
IAGP
MGI
PMID:12591907 PMID:16211006
NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346
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Cd200
CD200 molecule
IAGP
MGI
PMID:11099416
NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416
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Chd2
chromodomain helicase DNA binding protein 2
IAGP
MGI
PMID:16810678
NCBI chr 7:73,076,400...73,191,494
Ensembl chr 7:73,076,386...73,191,578
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Cpox
coproporphyrinogen oxidase
IAGP
MGI
PMID:28600349
NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
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Dcc
DCC netrin 1 receptor
IAGP
MGI
PMID:18033315
NCBI chr18:71,386,703...72,484,299
Ensembl chr18:71,386,705...72,484,140
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Dnase2a
deoxyribonuclease II alpha
IAGP
MGI
PMID:17066036
NCBI chr 8:85,635,384...85,638,332
Ensembl chr 8:85,635,189...85,649,544
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Epb41
erythrocyte membrane protein band 4.1
IAGP
MGI
PMID:9927493
NCBI chr 4:131,650,724...131,802,824
Ensembl chr 4:131,650,724...131,802,632
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Fads2
fatty acid desaturase 2
IAGP
MGI
PMID:19351970
NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
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Flt3
FMS-like tyrosine kinase 3
IAGP
MGI
PMID:17936561
NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
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Foxp3
forkhead box P3
IAGP
MGI
PMID:2053595 PMID:2320565
NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484
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Ggct
gamma-glutamyl cyclotransferase
IAGP
MGI
PMID:34409610
NCBI chr 6:54,962,080...54,969,947
Ensembl chr 6:54,959,565...54,969,935
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Gt(ROSA)26Sor
gene trap ROSA 26, Philippe Soriano
IAGP
MGI
PMID:17875932 PMID:26438359
NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
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Hip1
huntingtin interacting protein 1
IAGP
MGI
PMID:19647224
NCBI chr 5:135,435,350...135,574,167
Ensembl chr 5:135,435,385...135,573,974
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Hk1
hexokinase 1
IAGP
MGI
PMID:11783948
NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687
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Hp
haptoglobin
IAGP
MGI
PMID:12393471
NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
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Hpx
hemopexin
IAGP
MGI
PMID:12393471
NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344
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Ifnar1
interferon (alpha and beta) receptor 1
IAGP
MGI
PMID:17066036
NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
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Il10
interleukin 10
IAGP
MGI
PMID:16476050
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Irf8
interferon regulatory factor 8
IAGP
MGI
PMID:8861914
NCBI chr 8:121,463,097...121,483,433
Ensembl chr 8:121,463,097...121,483,433
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Jak2
Janus kinase 2
IAGP
MGI
PMID:20472827 PMID:22144185
NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
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Kif15
kinesin family member 15
IAGP
MGI
PMID:36934586
NCBI chr 9:122,780,146...122,847,798
Ensembl chr 9:122,780,111...122,847,798
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Kmt2a
lysine (K)-specific methyltransferase 2A
IAGP
MGI
PMID:15635450
NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
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Kras
Kirsten rat sarcoma viral oncogene homolog
IAGP
MGI
PMID:14966562
NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
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Lgals2
lectin, galactose-binding, soluble 2
IAGP
MGI
PMID:23118208
NCBI chr15:78,735,060...78,739,729
Ensembl chr15:78,735,060...78,739,729
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Mpl
myeloproliferative leukemia virus oncogene
IAGP
MGI
PMID:15071178
NCBI chr 4:118,299,609...118,314,771
Ensembl chr 4:118,299,612...118,314,710
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Mybl1
myeloblastosis oncogene-like 1
IAGP
MGI
PMID:11207276
NCBI chr 1:9,737,632...9,770,664
Ensembl chr 1:9,737,640...9,770,434
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Nabp2
nucleic acid binding protein 2
IAGP
MGI
PMID:23459151
NCBI chr10:128,237,263...128,247,426
Ensembl chr10:128,237,264...128,247,361
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Ncstn
nicastrin
IAGP
MGI
PMID:21562564
NCBI chr 1:171,893,580...171,910,356
Ensembl chr 1:171,893,580...171,910,362
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Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
IAGP
MGI
PMID:18025196
NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
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Nmnat3
nicotinamide nucleotide adenylyltransferase 3
IAGP
MGI
PMID:24739386
NCBI chr 9:98,169,487...98,302,586
Ensembl chr 9:98,169,488...98,302,491
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Notch1
notch 1
IAGP
MGI
PMID:21562564
NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
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Notch2
notch 2
IAGP
MGI
PMID:21562564
NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
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Notch3
notch 3
IAGP
MGI
PMID:21562564
NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826
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Pgm3
phosphoglucomutase 3
IAGP
MGI
PMID:17548465
NCBI chr 9:86,423,997...86,453,927
Ensembl chr 9:86,436,430...86,453,895
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Prdx2
peroxiredoxin 2
IAGP
MGI
PMID:12586629
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
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Prf1
perforin 1 (pore forming protein)
IAGP
MGI
PMID:15069016
NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
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Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
IAGP
MGI
PMID:27666489
NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567
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Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
IAGP
MGI
PMID:20881209
NCBI chr15:98,710,678...98,729,354
Ensembl chr15:98,710,678...98,729,402
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Procr
protein C receptor, endothelial
IAGP
MGI
PMID:26045607
NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391
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Ptpn2
protein tyrosine phosphatase, non-receptor type 2
IAGP
MGI
PMID:9271584
NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665
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Ptprc
protein tyrosine phosphatase receptor type C
IAGP
MGI
PMID:11163182
NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
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Rasa3
RAS p21 protein activator 3
IAGP
MGI
PMID:22773809
NCBI chr 8:13,617,218...13,727,590
Ensembl chr 8:13,616,948...13,727,603
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Rbm15
RNA binding motif protein 15
IAGP
MGI
PMID:17376872 PMID:19542301
NCBI chr 3:107,212,827...107,244,102
Ensembl chr 3:107,232,737...107,240,989
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Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
IAGP
MGI
PMID:7834753
NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
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Ripk1
receptor (TNFRSF)-interacting serine-threonine kinase 1
IAGP
MGI
PMID:9529147
NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
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Runx1
runt related transcription factor 1
IAGP
MGI
PMID:16247465 PMID:19647224
NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
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Sele
selectin, endothelial cell
IAGP
MGI
PMID:8598043
NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
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Selp
selectin, platelet
IAGP
MGI
PMID:8598043
NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
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Sf3b1
splicing factor 3b, subunit 1
IAGP
MGI
PMID:25481243
NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640
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Sh3bp2
SH3-domain binding protein 2
IAGP
MGI
PMID:17218256
NCBI chr 5:34,683,128...34,720,983
Ensembl chr 5:34,683,182...34,720,985
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Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
IAGP
MGI
PMID:15849611
NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953
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Slc4a4
solute carrier family 4 (anion exchanger), member 4
IAGP
MGI
PMID:17192275
NCBI chr 5:88,941,717...89,387,515
Ensembl chr 5:89,034,345...89,387,512
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Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
IAGP
MGI
PMID:32504080
NCBI chr14:54,606,899...54,657,525
Ensembl chr14:54,606,899...54,655,237
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Socs1
suppressor of cytokine signaling 1
IAGP
MGI
PMID:9826711
NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
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Sos1
SOS Ras/Rac guanine nucleotide exchange factor 1
IAGP
MGI
PMID:21041952
NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882
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Sox9
SRY (sex determining region Y)-box 9
IAGP
MGI
PMID:19201862
NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
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Sptb
spectrin beta, erythrocytic
IAGP
MGI
PMID:9373273
NCBI chr12:76,627,262...76,757,321
Ensembl chr12:76,627,262...76,757,321
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Stim1
stromal interaction molecule 1
IAGP
MGI
PMID:17965774
NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526
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Tet2
tet methylcytosine dioxygenase 2
IAGP
MGI
PMID:21723201
NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900
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Tnfsf11
tumor necrosis factor (ligand) superfamily, member 11
IAGP
MGI
PMID:22836362
NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
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Tnip1
TNFAIP3 interacting protein 1
IAGP
MGI
PMID:21606507
NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743
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Tpp2
tripeptidyl peptidase II
IAGP
MGI
PMID:18362329
NCBI chr 1:43,973,130...44,042,160
Ensembl chr 1:43,972,807...44,042,160
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Ttc7
tetratricopeptide repeat domain 7
IAGP
MGI
PMID:16093647
NCBI chr17:87,590,328...87,689,197
Ensembl chr17:87,590,314...87,689,197
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Uros
uroporphyrinogen III synthase
IAGP
MGI
PMID:16314073
NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801
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Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor
IAGP
MGI
PMID:16476050
NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
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Vhl
von Hippel-Lindau tumor suppressor
IAGP
MGI
PMID:17992257
NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594
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Wipf1
WAS/WASL interacting protein family, member 1
IAGP
MGI
PMID:17086554
NCBI chr 2:73,259,954...73,359,831
Ensembl chr 2:73,259,954...73,360,078
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Zfpm1
zinc finger protein, multitype 1
IAGP
MGI
PMID:20010697
NCBI chr 8:123,008,595...123,064,601
Ensembl chr 8:123,008,880...123,063,990
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