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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased spleen red pulp amount
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Accession:MP:0008476 term browser browse the term
Definition:increase in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation
Synonyms:exact_synonym: increased splenic red pulp



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increased spleen red pulp amount term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 a disintegrin and metallopeptidase domain 10 IAGP MGI PMID:22042698 NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 IAGP MGI PMID:19201862 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
JBrowse link
G Akap12 A kinase anchor protein 12 IAGP MGI PMID:18593908 NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470
JBrowse link
G Asl argininosuccinate lyase IAGP MGI PMID:22081021 NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088
JBrowse link
G Bak1 BCL2-antagonist/killer 1 IAGP MGI PMID:11163212 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein IAGP MGI PMID:11163212 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like IAGP MGI PMID:17420462 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326
JBrowse link
G Cbl Casitas B-lineage lymphoma IAGP MGI PMID:12591907 PMID:16211006 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346
JBrowse link
G Cd200 CD200 molecule IAGP MGI PMID:11099416 NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 IAGP MGI PMID:16810678 NCBI chr 7:73,076,400...73,191,494
Ensembl chr 7:73,076,386...73,191,578
JBrowse link
G Cpox coproporphyrinogen oxidase IAGP MGI PMID:28600349 NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
JBrowse link
G Dcc DCC netrin 1 receptor IAGP MGI PMID:18033315 NCBI chr18:71,386,703...72,484,299
Ensembl chr18:71,386,705...72,484,140
JBrowse link
G Dnase2a deoxyribonuclease II alpha IAGP MGI PMID:17066036 NCBI chr 8:85,635,384...85,638,332
Ensembl chr 8:85,635,189...85,649,544
JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 IAGP MGI PMID:9927493 NCBI chr 4:131,650,724...131,802,824
Ensembl chr 4:131,650,724...131,802,632
JBrowse link
G Fads2 fatty acid desaturase 2 IAGP MGI PMID:19351970 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
JBrowse link
G Flt3 FMS-like tyrosine kinase 3 IAGP MGI PMID:17936561 NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:2053595 PMID:2320565 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Ggct gamma-glutamyl cyclotransferase IAGP MGI PMID:34409610 NCBI chr 6:54,962,080...54,969,947
Ensembl chr 6:54,959,565...54,969,935
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:17875932 PMID:26438359 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Hip1 huntingtin interacting protein 1 IAGP MGI PMID:19647224 NCBI chr 5:135,435,350...135,574,167
Ensembl chr 5:135,435,385...135,573,974
JBrowse link
G Hk1 hexokinase 1 IAGP MGI PMID:11783948 NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687
JBrowse link
G Hp haptoglobin IAGP MGI PMID:12393471 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hpx hemopexin IAGP MGI PMID:12393471 NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:17066036 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:16476050 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Irf8 interferon regulatory factor 8 IAGP MGI PMID:8861914 NCBI chr 8:121,463,097...121,483,433
Ensembl chr 8:121,463,097...121,483,433
JBrowse link
G Jak2 Janus kinase 2 IAGP MGI PMID:20472827 PMID:22144185 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Kif15 kinesin family member 15 IAGP MGI PMID:36934586 NCBI chr 9:122,780,146...122,847,798
Ensembl chr 9:122,780,111...122,847,798
JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A IAGP MGI PMID:15635450 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:14966562 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Lgals2 lectin, galactose-binding, soluble 2 IAGP MGI PMID:23118208 NCBI chr15:78,735,060...78,739,729
Ensembl chr15:78,735,060...78,739,729
JBrowse link
G Mpl myeloproliferative leukemia virus oncogene IAGP MGI PMID:15071178 NCBI chr 4:118,299,609...118,314,771
Ensembl chr 4:118,299,612...118,314,710
JBrowse link
G Mybl1 myeloblastosis oncogene-like 1 IAGP MGI PMID:11207276 NCBI chr 1:9,737,632...9,770,664
Ensembl chr 1:9,737,640...9,770,434
JBrowse link
G Nabp2 nucleic acid binding protein 2 IAGP MGI PMID:23459151 NCBI chr10:128,237,263...128,247,426
Ensembl chr10:128,237,264...128,247,361
JBrowse link
G Ncstn nicastrin IAGP MGI PMID:21562564 NCBI chr 1:171,893,580...171,910,356
Ensembl chr 1:171,893,580...171,910,362
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 IAGP MGI PMID:18025196 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 IAGP MGI PMID:24739386 NCBI chr 9:98,169,487...98,302,586
Ensembl chr 9:98,169,488...98,302,491
JBrowse link
G Notch1 notch 1 IAGP MGI PMID:21562564 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
JBrowse link
G Notch2 notch 2 IAGP MGI PMID:21562564 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
JBrowse link
G Notch3 notch 3 IAGP MGI PMID:21562564 NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826
JBrowse link
G Pgm3 phosphoglucomutase 3 IAGP MGI PMID:17548465 NCBI chr 9:86,423,997...86,453,927
Ensembl chr 9:86,436,430...86,453,895
JBrowse link
G Prdx2 peroxiredoxin 2 IAGP MGI PMID:12586629 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:15069016 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit IAGP MGI PMID:27666489 NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567
JBrowse link
G Prkag1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit IAGP MGI PMID:20881209 NCBI chr15:98,710,678...98,729,354
Ensembl chr15:98,710,678...98,729,402
JBrowse link
G Procr protein C receptor, endothelial IAGP MGI PMID:26045607 NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 IAGP MGI PMID:9271584 NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IAGP MGI PMID:11163182 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
JBrowse link
G Rasa3 RAS p21 protein activator 3 IAGP MGI PMID:22773809 NCBI chr 8:13,617,218...13,727,590
Ensembl chr 8:13,616,948...13,727,603
JBrowse link
G Rbm15 RNA binding motif protein 15 IAGP MGI PMID:17376872 PMID:19542301 NCBI chr 3:107,212,827...107,244,102
Ensembl chr 3:107,232,737...107,240,989
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B IAGP MGI PMID:7834753 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 IAGP MGI PMID:9529147 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
JBrowse link
G Runx1 runt related transcription factor 1 IAGP MGI PMID:16247465 PMID:19647224 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Sele selectin, endothelial cell IAGP MGI PMID:8598043 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Selp selectin, platelet IAGP MGI PMID:8598043 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 IAGP MGI PMID:25481243 NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640
JBrowse link
G Sh3bp2 SH3-domain binding protein 2 IAGP MGI PMID:17218256 NCBI chr 5:34,683,128...34,720,983
Ensembl chr 5:34,683,182...34,720,985
JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 IAGP MGI PMID:15849611 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953
JBrowse link
G Slc4a4 solute carrier family 4 (anion exchanger), member 4 IAGP MGI PMID:17192275 NCBI chr 5:88,941,717...89,387,515
Ensembl chr 5:89,034,345...89,387,512
JBrowse link
G Slc7a7 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 IAGP MGI PMID:32504080 NCBI chr14:54,606,899...54,657,525
Ensembl chr14:54,606,899...54,655,237
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IAGP MGI PMID:9826711 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IAGP MGI PMID:21041952 NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IAGP MGI PMID:19201862 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Sptb spectrin beta, erythrocytic IAGP MGI PMID:9373273 NCBI chr12:76,627,262...76,757,321
Ensembl chr12:76,627,262...76,757,321
JBrowse link
G Stim1 stromal interaction molecule 1 IAGP MGI PMID:17965774 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 IAGP MGI PMID:21723201 NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 IAGP MGI PMID:22836362 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 IAGP MGI PMID:21606507 NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743
JBrowse link
G Tpp2 tripeptidyl peptidase II IAGP MGI PMID:18362329 NCBI chr 1:43,973,130...44,042,160
Ensembl chr 1:43,972,807...44,042,160
JBrowse link
G Ttc7 tetratricopeptide repeat domain 7 IAGP MGI PMID:16093647 NCBI chr17:87,590,328...87,689,197
Ensembl chr17:87,590,314...87,689,197
JBrowse link
G Uros uroporphyrinogen III synthase IAGP MGI PMID:16314073 NCBI chr 7:133,287,871...133,312,176
Ensembl chr 7:133,287,972...133,311,801
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor IAGP MGI PMID:16476050 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor IAGP MGI PMID:17992257 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594
JBrowse link
G Wipf1 WAS/WASL interacting protein family, member 1 IAGP MGI PMID:17086554 NCBI chr 2:73,259,954...73,359,831
Ensembl chr 2:73,259,954...73,360,078
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 IAGP MGI PMID:20010697 NCBI chr 8:123,008,595...123,064,601
Ensembl chr 8:123,008,880...123,063,990
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    hematopoietic system phenotype 5543
      abnormal hematopoietic system morphology/development 5069
        abnormal spleen morphology 1819
          abnormal spleen red pulp morphology 155
            increased spleen red pulp amount 75
Path 2
Term Annotations click to browse term
  mammalian phenotype 16965
    immune system phenotype 5709
      abnormal immune system morphology 4077
        abnormal immune system organ morphology 2439
          abnormal spleen morphology 1819
            abnormal spleen red pulp morphology 155
              increased spleen red pulp amount 75
paths to the root