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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased gamma-delta T cell number
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Accession:MP:0008347 term browser browse the term
Definition:reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex
Comment:Note that gamma-delta T cell have both thymic and extrathymic differentiation pathways.
Synonyms:exact_synonym: decreased gamma-delta T lymphocyte number;   reduced gamma-delta T-cell number;   reduced gamma-delta T-lymphocyte number


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decreased gamma-delta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700016L21Rik RIKEN cDNA 1700016L21 gene IAGP MGI PMID:23064362 NCBI chr 1:80,423,649...80,453,377
Ensembl chr 1:80,317,232...80,477,001 		JBrowse link
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a IAGP MGI PMID:28085150 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b IAGP MGI PMID:28085150 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d IAGP MGI PMID:28085150 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:19260764 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit IEA MGI NCBI chr17:57,297,264...57,303,371
Ensembl chr17:57,297,305...57,303,188 		JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:21258009 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351 		JBrowse link
G Ctnnb1 catenin beta 1 IAGP MGI PMID:23918954 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Dntt deoxynucleotidyltransferase, terminal IAGP MGI PMID:10792495 NCBI chr19:41,017,701...41,047,964
Ensembl chr19:41,017,714...41,047,964 		JBrowse link
G Fyn Fyn proto-oncogene IAGP MGI PMID:8934569 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G Gata3 GATA binding protein 3 IAGP MGI PMID:19934022 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22770884 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G H2-Q10 histocompatibility 2, Q region locus 10 IAGP MGI PMID:30537346 NCBI chr17:35,780,986...35,785,460
Ensembl chr17:35,780,986...35,785,460 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 IAGP MGI PMID:21093323 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614 		JBrowse link
G Il1rl2 interleukin 1 receptor-like 2 IAGP MGI PMID:23064362 NCBI chr 1:40,363,697...40,406,722
Ensembl chr 1:40,363,770...40,406,722 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 IAGP MGI PMID:23064362 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Jag2 jagged 2 IAGP MGI PMID:9531541 NCBI chr12:112,871,439...112,893,437
Ensembl chr12:112,871,439...112,893,396 		JBrowse link
G Krt14 keratin 14 IAGP MGI PMID:23918954 NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374 		JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 IAGP MGI PMID:21419662 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824 		JBrowse link
G Nlk nemo like kinase IAGP MGI PMID:11745377 NCBI chr11:78,457,994...78,588,848
Ensembl chr11:78,457,994...78,588,199 		JBrowse link
G Pole3 polymerase (DNA directed), epsilon 3 (p17 subunit) IAGP MGI PMID:32553171 NCBI chr 4:62,440,889...62,443,305
Ensembl chr 4:62,440,886...62,443,305 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:21482716 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:19126872 PMID:22770884 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Rnf168 ring finger protein 168 IAGP MGI PMID:21552324 NCBI chr16:32,096,279...32,120,260
Ensembl chr16:32,096,277...32,120,252 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IAGP MGI PMID:21746917 NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882 		JBrowse link
G Sox13 SRY (sex determining region Y)-box 13 IAGP MGI PMID:17218525 NCBI chr 1:133,310,038...133,352,159
Ensembl chr 1:133,310,041...133,352,115 		JBrowse link
G Trappc9 trafficking protein particle complex 9 IEA MGI NCBI chr15:72,461,469...72,933,086
Ensembl chr15:72,461,469...72,933,053 		JBrowse link
G Trdc T cell receptor delta, constant region IAGP MGI PMID:22770884 NCBI chr14:54,380,308...54,383,565
Ensembl chr14:54,380,308...54,386,325 		JBrowse link
G Trgc1 T cell receptor gamma, constant 1 IAGP MGI PMID:15345225 NCBI chr13:19,398,273...19,400,788
Ensembl chr13:19,398,273...19,401,194 		JBrowse link
G Wls wntless WNT ligand secretion mediator IAGP MGI PMID:23918954 NCBI chr 3:159,545,287...159,644,302
Ensembl chr 3:159,545,309...159,644,300 		JBrowse link
G Zbtb17 zinc finger and BTB domain containing 17 IAGP MGI PMID:21258009 NCBI chr 4:141,171,984...141,195,248
Ensembl chr 4:141,171,965...141,195,241 		JBrowse link
absent gamma-delta intraepithelial T cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 CD247 antigen IAGP MGI PMID:9529325 NCBI chr 1:165,607,514...165,698,722
Ensembl chr 1:165,616,250...165,704,846 		JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide IAGP MGI PMID:9529325 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934 		JBrowse link
G Il2rg interleukin 2 receptor, gamma chain IAGP MGI PMID:7697543 PMID:9334367 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861 		JBrowse link
absent gamma-delta T cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22770884 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Il17a interleukin 17A IAGP MGI PMID:22770884 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il17f interleukin 17F IAGP MGI PMID:22770884 NCBI chr 1:20,847,370...20,855,498
Ensembl chr 1:20,847,370...20,860,841 		JBrowse link
G Il2rg interleukin 2 receptor, gamma chain IAGP MGI PMID:7697543 PMID:9334367 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861 		JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:22770884 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:17617584 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874 		JBrowse link
G Tcra T cell receptor alpha chain IAGP MGI PMID:17617584 PMID:18242214 NCBI chr14:52,665,424...54,461,655 JBrowse link
G Tcrb T cell receptor beta chain IAGP MGI PMID:17617584 NCBI chr 6:40,868,230...41,535,305 JBrowse link
G Tcrd T cell receptor delta chain IAGP MGI PMID:8381716 NCBI chr14:54,183,530...54,396,655 JBrowse link
G Tcrg T cell receptor gamma chain IAGP MGI PMID:18242214 NCBI chr13:19,362,212...19,540,646 JBrowse link
G Trdc T cell receptor delta, constant region IAGP MGI PMID:22770884 NCBI chr14:54,380,308...54,383,565
Ensembl chr14:54,380,308...54,386,325 		JBrowse link
absent mature gamma-delta T cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il7r interleukin 7 receptor IAGP MGI PMID:8692964 NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262 		JBrowse link
G Lat linker for activation of T cells IAGP MGI PMID:12970761 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742 		JBrowse link
decreased CD4-positive, gamma-delta intraepithelial T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btnl6 butyrophilin-like 6 IAGP MGI PMID:32724083 NCBI chr17:34,726,844...34,737,750
Ensembl chr17:34,726,778...34,736,326 		JBrowse link
decreased CD5-positive gamma-delta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
decreased CD8-positive, gamma-delta intraepithelial T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr9 C-C motif chemokine receptor 9 IAGP MGI PMID:11884450 NCBI chr 9:123,596,276...123,612,522
Ensembl chr 9:123,507,504...123,613,395 		JBrowse link
G Gpr18 G protein-coupled receptor 18 IAGP MGI PMID:25348153 NCBI chr14:122,148,846...122,153,300
Ensembl chr14:122,148,665...122,153,193 		JBrowse link
G Il15 interleukin 15 IAGP MGI PMID:19913445 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il15ra interleukin 15 receptor, alpha chain IAGP MGI PMID:19913445 NCBI chr 2:11,709,992...11,739,129
Ensembl chr 2:11,710,101...11,739,128 		JBrowse link
decreased dendritic epidermal T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mkrn2 makorin, ring finger protein, 2 IEA MGI NCBI chr 6:115,578,844...115,598,647
Ensembl chr 6:115,578,863...115,599,585 		JBrowse link
G Skint2 selection and upkeep of intraepithelial T cells 2 IAGP MGI PMID:32724083 NCBI chr 4:112,470,917...112,509,447
Ensembl chr 4:112,414,391...112,509,445 		JBrowse link
G Zdhhc2 zinc finger, DHHC domain containing 2 IAGP MGI PMID:33488612 NCBI chr 8:40,876,526...40,946,178
Ensembl chr 8:40,876,856...40,963,309 		JBrowse link
decreased gamma-delta intraepithelial T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A IAGP MGI PMID:10906391 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B IAGP MGI PMID:10906391 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Btnl1 butyrophilin-like 1 IAGP MGI PMID:27641500 NCBI chr17:34,596,097...34,605,136
Ensembl chr17:34,596,106...34,605,002 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 IAGP MGI PMID:17548595 PMID:18439426 NCBI chr 8:4,375,207...4,410,020
Ensembl chr 8:4,375,210...4,410,020 		JBrowse link
G Ccr10 C-C motif chemokine receptor 10 IAGP MGI PMID:20937851 NCBI chr11:101,063,824...101,066,269
Ensembl chr11:101,063,823...101,066,269 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 IAGP MGI PMID:17548595 PMID:18439426 NCBI chr 9:123,596,276...123,612,522
Ensembl chr 9:123,507,504...123,613,395 		JBrowse link
G Foxn1 forkhead box N1 IAGP MGI PMID:15699117 PMID:27641500 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384 		JBrowse link
G Fyn Fyn proto-oncogene IAGP MGI PMID:8934570 PMID:9045930 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:27641500 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:7923373 PMID:8986714 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IAGP MGI PMID:15699117 NCBI chr11:103,110,590...103,158,227
Ensembl chr11:103,110,588...103,158,298 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IAGP MGI PMID:9725213 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:18439426 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
decreased mature gamma-delta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:8986714 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Nckap1l NCK associated protein 1 like IAGP MGI PMID:19015308 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
decreased memory-marker gamma-delta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef1 Rho guanine nucleotide exchange factor 1 IEA MGI NCBI chr 7:24,601,762...24,626,019
Ensembl chr 7:24,602,337...24,626,019 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,088
Ensembl chr 2:122,129,381...122,133,366 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17094
    hematopoietic system phenotype 5612
      abnormal hematopoietic system morphology/development 5135
        abnormal hematopoietic cell morphology 4314
          abnormal leukocyte morphology 2896
            abnormal leukocyte cell number 2606
              abnormal lymphocyte cell number 1738
                abnormal T cell number 1090
                  decreased T cell number 783
                    decreased gamma-delta T cell number 66
                      absent gamma-delta T cells 11
                      decreased CD5-positive gamma-delta T cell number 1
                      decreased KLRG1-positive gamma-delta T cell number 0
                      decreased dendritic epidermal T cell number 3
                      decreased mature gamma-delta T cell number + 23
                      decreased memory-marker gamma-delta T cell number 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 17094
    immune system phenotype 5782
      abnormal immune system morphology 4140
        abnormal immune system cell morphology 2915
          abnormal leukocyte morphology 2896
            abnormal mononuclear cell morphology 2315
              abnormal lymphocyte morphology 1876
                abnormal lymphocyte cell number 1738
                  abnormal T cell number 1090
                    decreased T cell number 783
                      decreased gamma-delta T cell number 66
                        absent gamma-delta T cells 11
                        decreased CD5-positive gamma-delta T cell number 1
                        decreased KLRG1-positive gamma-delta T cell number 0
                        decreased dendritic epidermal T cell number 3
                        decreased mature gamma-delta T cell number + 23
                        decreased memory-marker gamma-delta T cell number 3
paths to the root