abnormal metallophilic macrophage morphology - Ontology Report - Rat Genome Database

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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	abnormal metallophilic macrophage morphology	go back to main search page
Accession:	MP:0008241	browse the term
Definition:	any structural anomaly of the macrophage cells that surround the white pulp of the spleen, adjacent to the marginal sinus
Comment:	Metallophilic macrophage cells express the cell surface protein Siglec1 (also called CD169 or sialoadhesin), which is often detected with the MOMA-1 antibody.
Synonyms:	exact_synonym:	abnormal MOMA-1 positive cells; abnormal marginal metallophilic macrophage; abnormal splenic marginal metallophilic macrophages; abnormal splenic metallophilic macrophage morphology

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Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5373
hematopoietic system phenotype	243
abnormal hematopoietic system morphology/development	223
abnormal spleen morphology	33
abnormal spleen white pulp morphology	3
abnormal metallophilic macrophage morphology	0
Path 2
Term	Annotations
mammalian phenotype	5373
hematopoietic system phenotype	243
abnormal hematopoietic system morphology/development	223
abnormal hematopoietic cell morphology	179
abnormal leukocyte morphology	147
abnormal myeloid leukocyte morphology	64
abnormal phagocyte morphology	41
abnormal mononuclear phagocyte morphology	36
abnormal macrophage morphology	30
abnormal metallophilic macrophage morphology	0

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