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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal metallophilic macrophage morphology
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Accession:MP:0008241 term browser browse the term
Definition:any structural anomaly of the macrophage cells that surround the white pulp of the spleen, adjacent to the marginal sinus
Comment:Metallophilic macrophage cells express the cell surface protein Siglec1 (also called CD169 or sialoadhesin), which is often detected with the MOMA-1 antibody.
Synonyms:exact_synonym: abnormal MOMA-1 positive cells;   abnormal marginal metallophilic macrophage;   abnormal splenic marginal metallophilic macrophages;   abnormal splenic metallophilic macrophage morphology



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal spleen morphology 33
          abnormal spleen white pulp morphology 3
            abnormal metallophilic macrophage morphology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal leukocyte morphology 154
            abnormal myeloid leukocyte morphology 70
              abnormal phagocyte morphology 47
                abnormal mononuclear phagocyte morphology 42
                  abnormal macrophage morphology 36
                    abnormal metallophilic macrophage morphology 0
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