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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased susceptibility to neuronal excitotoxicity
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Accession:MP:0008236 term browser browse the term
Definition:less than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kainate-induced neuronal cell death mediated via a glutamate excitotoxic process
Synonyms:exact_synonym: decreased susceptibility to neurotoxicity-induced cell death;   increased resistance to neuronal excitotoxicity;   reduced susceptibility to neuronal excitotoxicity



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decreased susceptibility to neuronal excitotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha IMP RGD PMID:16837598 RGD:13506279 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5373
    homeostasis/metabolism phenotype 1396
      abnormal physiological response to xenobiotic 28
        decreased physiological sensitivity to xenobiotic 15
          decreased susceptibility to neuronal excitotoxicity 2
            decreased susceptibility to dopaminergic neuron neurotoxicity 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5373
    cellular phenotype 175
      abnormal cell physiology 139
        abnormal cell death 59
          abnormal apoptosis 43
            abnormal neuron apoptosis 3
              decreased neuron apoptosis 3
                decreased susceptibility to neuronal excitotoxicity 2
                  decreased susceptibility to dopaminergic neuron neurotoxicity 0
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