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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased susceptibility to neuronal excitotoxicity
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Accession:MP:0008236 term browser browse the term
Definition:less than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kainate-induced neuronal cell death mediated via a glutamate excitotoxic process
Synonyms:exact_synonym: decreased susceptibility to neurotoxicity-induced cell death;   increased resistance to neuronal excitotoxicity;   reduced susceptibility to neuronal excitotoxicity



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decreased susceptibility to neuronal excitotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha IMP RGD PMID:16837598 RGD:13506279 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    homeostasis/metabolism phenotype 1418
      abnormal physiological response to xenobiotic 28
        decreased physiological sensitivity to xenobiotic 15
          decreased susceptibility to neuronal excitotoxicity 2
            decreased susceptibility to dopaminergic neuron neurotoxicity 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell physiology 145
        abnormal cell death 58
          abnormal programmed cell death 42
            abnormal apoptosis 42
              abnormal neuron apoptosis 3
                decreased neuron apoptosis 3
                  decreased susceptibility to neuronal excitotoxicity 2
                    decreased susceptibility to dopaminergic neuron neurotoxicity 0
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