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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased susceptibility to neuronal excitotoxicity
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Accession:MP:0008236 term browser browse the term
Definition:less than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kainate-induced neuronal cell death mediated via a glutamate excitotoxic process
Synonyms:exact_synonym: decreased susceptibility to neurotoxicity-induced cell death;   increased resistance to neuronal excitotoxicity;   reduced susceptibility to neuronal excitotoxicity


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decreased susceptibility to neuronal excitotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S HotHsd:SD Sprague Dawley IAGP compared to Wistar rat RGD PMID:17804792 RGD:13524860
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5372
    homeostasis/metabolism phenotype 1393
      abnormal physiological response to xenobiotic 27
        decreased physiological sensitivity to xenobiotic 14
          decreased susceptibility to neuronal excitotoxicity 1
            decreased susceptibility to dopaminergic neuron neurotoxicity 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5372
    cellular phenotype 174
      abnormal cell physiology 138
        abnormal cell death 58
          abnormal apoptosis 42
            abnormal neuron apoptosis 2
              decreased neuron apoptosis 2
                decreased susceptibility to neuronal excitotoxicity 1
                  decreased susceptibility to dopaminergic neuron neurotoxicity 0
paths to the root