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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased immature B cell number
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Accession:MP:0008214 term browser browse the term
Definition:greater number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity
Synonyms:exact_synonym: increased number of immature B cells;   increased number of immature B-lymphocytes



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increased immature B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IAGP MGI PMID:9647203 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Atmin ATM interactor IAGP MGI PMID:22891272 NCBI chr 8:117,670,132...117,687,184
Ensembl chr 8:117,670,132...117,687,184
JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 IAGP MGI PMID:21606958 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l11 BCL2 like 11 IAGP MGI PMID:18275831 PMID:18299399 PMID:22891272 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bmf BCL2 modifying factor IAGP MGI PMID:18299399 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168
JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase IEA MGI NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:20705491 PMID:25238757 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd69 CD69 antigen IAGP MGI PMID:10733501 NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
JBrowse link
G Cd72 CD72 antigen IAGP MGI PMID:10549631 NCBI chr 4:43,447,724...43,454,708
Ensembl chr 4:43,446,462...43,454,628
JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) IAGP MGI PMID:10384121 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21841126 PMID:22891272 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Def6 differentially expressed in FDCP 6 IAGP MGI PMID:16470246 NCBI chr17:28,426,752...28,447,582
Ensembl chr17:28,426,752...28,447,582
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 IAGP MGI PMID:18513163 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
JBrowse link
G Dll4 delta like canonical Notch ligand 4 IAGP MGI PMID:18824585 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443
JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IAGP MGI PMID:22431588 NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 IAGP MGI PMID:25238757 NCBI chr13:75,855,603...75,920,480
Ensembl chr13:75,854,876...75,920,483
JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:18275831 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fnip1 folliculin interacting protein 1 IAGP MGI PMID:22709692 NCBI chr11:54,328,071...54,409,067
Ensembl chr11:54,329,025...54,409,061
JBrowse link
G Foxn1 forkhead box N1 IAGP MGI PMID:18824585 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 IAGP MGI PMID:8046347 NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IAGP MGI PMID:21093323 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 IEA MGI NCBI chr 5:104,137,631...104,169,662
Ensembl chr 5:104,137,628...104,169,785
JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:12668643 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Igk immunoglobulin kappa chain complex IAGP MGI PMID:17546032 NCBI chr 6:67,532,620...70,703,738 JBrowse link
G Igkc immunoglobulin kappa constant IAGP MGI PMID:8458339 NCBI chr 6:70,703,419...70,703,738
Ensembl chr 6:70,703,419...70,703,950
JBrowse link
G Irf5 interferon regulatory factor 5 IAGP MGI PMID:22431588 NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870
JBrowse link
G Klhl6 kelch-like 6 IEA MGI NCBI chr16:19,765,242...19,801,766
Ensembl chr16:19,765,246...19,801,787
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IEA MGI NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:31126966 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:21333553 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Notch1 notch 1 IAGP MGI PMID:18824585 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
JBrowse link
G Plcg2 phospholipase C, gamma 2 IAGP MGI PMID:10925250 NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:14557749 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:14557749 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:12531919 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
JBrowse link
G Tcrb T cell receptor beta chain IAGP MGI PMID:22585710 NCBI chr 6:40,868,230...41,535,305 JBrowse link
G Tcrd T cell receptor delta chain IAGP MGI PMID:22585710 NCBI chr14:54,183,530...54,396,655 JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IAGP MGI PMID:20705491 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) IAGP MGI PMID:11160187 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfrsf13c tumor necrosis factor receptor superfamily, member 13c IAGP MGI PMID:21228330 NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570
JBrowse link
G Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b IEA MGI NCBI chr 8:10,056,637...10,086,000
Ensembl chr 8:10,056,467...10,089,072
JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IAGP MGI PMID:22585710 NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303
JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:14623913 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
G Vav2 vav 2 oncogene IAGP MGI PMID:14623913 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045
JBrowse link
G Vav3 vav 3 oncogene IAGP MGI PMID:14623913 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IAGP MGI PMID:11257140 PMID:11257141 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C IAGP MGI PMID:31126966 NCBI chr 9:52,020,869...52,080,028
Ensembl chr 9:52,022,644...52,079,872
JBrowse link
increased transitional stage B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 IAGP MGI PMID:16055554 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein IAGP MGI PMID:16055554 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2l11 BCL2 like 11 IAGP MGI PMID:16055554 PMID:18275831 PMID:18299399 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Blnk B cell linker IAGP MGI PMID:12119344 NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978
JBrowse link
G Bmf BCL2 modifying factor IAGP MGI PMID:18299399 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:16055554 PMID:17723217 PMID:21178004 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd36 CD36 molecule IAGP MGI PMID:18097024 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cd40 CD40 antigen IAGP MGI PMID:18624351 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:16860757 PMID:21841126 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IAGP MGI PMID:16973390 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 IAGP MGI PMID:18513163 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:18275831 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fli1 Friend leukemia integration 1 IAGP MGI PMID:18641300 NCBI chr 9:32,333,500...32,454,292
Ensembl chr 9:32,333,500...32,454,157
JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:12119344 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Igk immunoglobulin kappa chain complex IAGP MGI PMID:12119344 NCBI chr 6:67,532,620...70,703,738 JBrowse link
G Irf8 interferon regulatory factor 8 IAGP MGI PMID:21178004 NCBI chr 8:121,463,097...121,483,433
Ensembl chr 8:121,463,097...121,483,433
JBrowse link
G Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 IAGP MGI PMID:14688067 NCBI chr19:11,227,043...11,243,513
Ensembl chr19:11,227,039...11,243,605
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IAGP MGI PMID:16973390 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 IAGP MGI PMID:18025196 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma IAGP MGI PMID:16129705 NCBI chr12:55,327,594...55,350,024
Ensembl chr12:55,325,776...55,349,783
JBrowse link
G Prkcd protein kinase C, delta IAGP MGI PMID:16481047 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IAGP MGI PMID:19299707 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IAGP MGI PMID:19299707 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
JBrowse link
G Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b IAGP MGI PMID:11429549 NCBI chr11:61,017,567...61,040,435
Ensembl chr11:61,017,581...61,040,198
JBrowse link
G Traf3 TNF receptor-associated factor 3 IAGP MGI PMID:17723217 NCBI chr12:111,132,799...111,233,589
Ensembl chr12:111,132,804...111,233,587
JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IAGP MGI PMID:18624351 NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303
JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:11376343 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IAGP MGI PMID:11257141 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
increased transitional stage T1 B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 a disintegrin and metallopeptidase domain 10 IAGP MGI PMID:20156974 NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511
JBrowse link
G Akap13 A kinase anchor protein 13 IAGP MGI PMID:19211510 NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357
JBrowse link
G Arhgap17 Rho GTPase activating protein 17 IEA MGI NCBI chr 7:122,878,372...122,969,171
Ensembl chr 7:122,878,441...122,969,138
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:20156974 PMID:21795747 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21841126 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 IAGP MGI PMID:23226392 NCBI chr 4:109,137,372...109,245,014
Ensembl chr 4:109,137,465...109,245,014
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:21795747 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Lama5 laminin, alpha 5 IAGP MGI PMID:23847204 NCBI chr 2:179,818,166...179,867,652
Ensembl chr 2:179,818,166...179,867,652
JBrowse link
G Ppic peptidylprolyl isomerase C IAGP MGI PMID:33864384 NCBI chr18:53,539,413...53,551,079
Ensembl chr18:53,539,404...53,551,187
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IAGP MGI PMID:23619366 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563
JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:14623913 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
G Vav2 vav 2 oncogene IAGP MGI PMID:14623913 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045
JBrowse link
G Vav3 vav 3 oncogene IAGP MGI PMID:14623913 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014
JBrowse link
increased transitional stage T2 B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrg3 adhesion G protein-coupled receptor G3 IAGP MGI PMID:24113187 NCBI chr 8:95,743,742...95,771,878
Ensembl chr 8:95,744,320...95,771,878
JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:31784498 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21841126 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Niban3 niban apoptosis regulator 3 IAGP MGI PMID:31412363 NCBI chr 8:72,049,000...72,061,599
Ensembl chr 8:72,050,292...72,060,580
JBrowse link
G Plcg2 phospholipase C, gamma 2 IAGP MGI PMID:12928432 NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881
JBrowse link
G Ppic peptidylprolyl isomerase C IAGP MGI PMID:33864384 NCBI chr18:53,539,413...53,551,079
Ensembl chr18:53,539,404...53,551,187
JBrowse link
G Tcrb T cell receptor beta chain IAGP MGI PMID:22585710 NCBI chr 6:40,868,230...41,535,305 JBrowse link
G Tcrd T cell receptor delta chain IAGP MGI PMID:22585710 NCBI chr14:54,183,530...54,396,655 JBrowse link
increased transitional stage T3 B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21841126 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Tcrb T cell receptor beta chain IAGP MGI PMID:22585710 NCBI chr 6:40,868,230...41,535,305 JBrowse link
G Tcrd T cell receptor delta chain IAGP MGI PMID:22585710 NCBI chr14:54,183,530...54,396,655 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    immune system phenotype 5613
      abnormal immune system morphology 4014
        abnormal immune system cell morphology 2804
          abnormal leukopoiesis 863
            abnormal lymphopoiesis 740
              abnormal B cell differentiation 394
                abnormal immature B cell morphology 195
                  abnormal immature B cell number 187
                    increased immature B cell number 75
                      increased transitional stage B cell number + 43
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    hematopoietic system phenotype 5459
      abnormal hematopoietic system morphology/development 4999
        abnormal hematopoietic cell morphology 4182
          abnormal blood cell morphology 3154
            abnormal hemopoiesis 1149
              abnormal definitive hematopoiesis 1122
                abnormal leukopoiesis 863
                  abnormal lymphopoiesis 740
                    abnormal B cell differentiation 394
                      abnormal immature B cell morphology 195
                        abnormal immature B cell number 187
                          increased immature B cell number 75
                            increased transitional stage B cell number + 43
paths to the root