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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased mature B cell number
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Accession:MP:0008211 term browser browse the term
Definition:reduced number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex
Synonyms:exact_synonym: decreased number of mature B-cells;   decreased number of mature B-lymphocytes;   reduced mature B cell number


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decreased mature B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2rg interleukin 2 receptor subunit gamma IMP RGD PMID:29688994 RGD:13628403 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il2rgem1Ang interleukin 2 receptor subunit gamma;TALEN induced mutant1, Ang IMP RGD PMID:29688994 RGD:13628403
G Rag1 recombination activating 1 IMP RGD PMID:29688994 RGD:13628403 NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291 		JBrowse link
G Rag1em1Ang recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon IMP RGD PMID:29688994 RGD:13628403
absent mature B cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5374
    immune system phenotype 492
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal leukocyte cell number 134
              abnormal lymphocyte cell number 92
                abnormal B cell number 28
                  decreased B cell number 23
                    decreased mature B cell number 8
                      absent mature B cells 2
                      decreased B-1 B cell number + 0
                      decreased B-2 B cell number + 0
                      decreased follicular B cell number + 0
                      decreased germinal center B cell number + 0
                      decreased marginal zone B cell number + 0
                      decreased marginal zone precursor B cell number 0
                      decreased memory B cell number + 0
                      decreased plasma cell number + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5374
    immune system phenotype 492
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal mononuclear cell morphology 120
              abnormal lymphocyte morphology 98
                abnormal B cell morphology 28
                  abnormal B cell number 28
                    abnormal mature B cell number 11
                      decreased mature B cell number 8
                        absent mature B cells 2
                        decreased B-1 B cell number + 0
                        decreased B-2 B cell number + 0
                        decreased follicular B cell number + 0
                        decreased germinal center B cell number + 0
                        decreased marginal zone B cell number + 0
                        decreased marginal zone precursor B cell number 0
                        decreased memory B cell number + 0
                        decreased plasma cell number + 0
paths to the root