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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:absent B-1 B cells
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Accession:MP:0008202 term browser browse the term
Definition:absence of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and are enriched for self-reactivity; B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas


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Path 1
Term Annotations click to browse term
  mammalian phenotype 8
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system cell morphology 0
          abnormal professional antigen presenting cell morphology 0
            abnormal mature B cell morphology 0
              abnormal B-1 B cell morphology 0
                abnormal B-1 B cell number 0
                  decreased B-1 B cell number 0
                    absent B-1 B cells 0
                      absent B-1a cells 0
                      absent B-1b cells 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 8
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system cell morphology 0
          abnormal leukocyte morphology 0
            abnormal mononuclear cell morphology 0
              abnormal lymphocyte morphology 0
                abnormal B cell morphology 0
                  abnormal mature B cell morphology 0
                    abnormal B-1 B cell morphology 0
                      abnormal B-1 B cell number 0
                        decreased B-1 B cell number 0
                          absent B-1 B cells 0
                            absent B-1a cells 0
                            absent B-1b cells 0
paths to the root