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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:absent B-1 B cells
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Accession:MP:0008202 term browser browse the term
Definition:absence of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and are enriched for self-reactivity; B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5428
    immune system phenotype 519
      abnormal immune system morphology 211
        abnormal immune system cell morphology 150
          abnormal professional antigen presenting cell morphology 39
            abnormal mature B cell morphology 3
              abnormal B-1 B cell morphology 3
                abnormal B-1 B cell number 3
                  decreased B-1 B cell number 0
                    absent B-1 B cells 0
                      absent B-1a cells 0
                      absent B-1b cells 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5428
    immune system phenotype 519
      abnormal immune system morphology 211
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal mononuclear cell morphology 125
              abnormal lymphocyte morphology 97
                abnormal B cell morphology 29
                  abnormal mature B cell morphology 3
                    abnormal B-1 B cell morphology 3
                      abnormal B-1 B cell number 3
                        decreased B-1 B cell number 0
                          absent B-1 B cells 0
                            absent B-1a cells 0
                            absent B-1b cells 0
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