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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased B-1a cell number
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Accession:MP:0008168 term browser browse the term
Definition:reduced number of the B-1 B cell subset bearing the CD5 surface marker
Synonyms:exact_synonym: decreased number of B-1a cells;   reduced B-1a cell number


show annotations for term's descendants           Sort by:
decreased B-1a cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap17 Rho GTPase activating protein 17 IEA MGI NCBI chr 7:122,878,372...122,969,171
Ensembl chr 7:122,878,441...122,969,138 		JBrowse link
G Arid3a AT-rich interaction domain 3A IAGP MGI PMID:21199920 NCBI chr10:79,762,877...79,790,852
Ensembl chr10:79,762,877...79,790,852 		JBrowse link
G Atp11c ATPase, class VI, type 11C IAGP MGI PMID:21423173 NCBI chr  X:59,268,643...59,450,041
Ensembl chr  X:59,268,650...59,636,304 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Blnk B cell linker IAGP MGI PMID:10583957 NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:31784498 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:21341261 PMID:21795747 PMID:23509369 PMID:24242374 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061 		JBrowse link
G Cd22 CD22 antigen IAGP MGI PMID:17420268 NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767 		JBrowse link
G Cd6 CD6 antigen IAGP MGI PMID:27909060 NCBI chr19:10,766,703...10,807,427
Ensembl chr19:10,766,705...10,807,422 		JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:16818674 PMID:16860757 PMID:17420268 PMID:21464221 PMID:21708930 More... NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622 		JBrowse link
G Cd79b CD79B antigen IAGP MGI PMID:15024049 PMID:16818674 NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588 		JBrowse link
G Cd81 CD81 antigen IAGP MGI PMID:9380722 NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671 		JBrowse link
G Cdh17 cadherin 17 IAGP MGI PMID:15688343 NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895 		JBrowse link
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 IAGP MGI PMID:24080084 NCBI chr 9:114,585,904...114,611,061
Ensembl chr 9:114,585,904...114,610,924 		JBrowse link
G Cr2 complement receptor 2 IAGP MGI PMID:10779753 PMID:23733878 NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024 		JBrowse link
G Dapp1 dual adaptor for phosphotyrosine and 3-phosphoinositides 1 IAGP MGI PMID:14563325 NCBI chr 3:137,636,768...137,687,331
Ensembl chr 3:137,636,768...137,687,306 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IAGP MGI PMID:19103880 NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 IEA MGI NCBI chr13:55,300,631...55,316,572
Ensembl chr13:55,300,453...55,316,572 		JBrowse link
G Gimap1 GTPase, IMAP family member 1 IAGP MGI PMID:20194894 NCBI chr 6:48,715,981...48,720,729
Ensembl chr 6:48,715,988...48,720,729 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:21708930 PMID:21795747 PMID:24242374 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Hax1 HCLS1 associated X-1 IAGP MGI PMID:20865787 NCBI chr 3:89,902,753...89,906,023
Ensembl chr 3:89,902,753...89,906,087 		JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:16754718 PMID:17420268 PMID:19050258 PMID:21623346 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Igll1 immunoglobulin lambda-like polypeptide 1 IAGP MGI PMID:12055243 NCBI chr16:16,678,535...16,681,849
Ensembl chr16:16,678,535...16,681,849 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:11870616 PMID:24013668 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il6st interleukin 6 signal transducer IAGP MGI PMID:10661409 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Klhl14 kelch-like 14 IAGP MGI PMID:29939266 NCBI chr18:21,683,436...21,805,986
Ensembl chr18:21,683,434...21,787,775 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 IEA MGI NCBI chr13:41,463,392...41,640,836
Ensembl chr13:41,463,057...41,640,838 		JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 IAGP MGI PMID:21464221 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IEA MGI NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkbid nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta IAGP MGI PMID:22761313 NCBI chr 7:30,121,156...30,128,173
Ensembl chr 7:30,121,157...30,128,171 		JBrowse link
G Niban3 niban apoptosis regulator 3 IAGP MGI PMID:31412363 NCBI chr 8:72,049,000...72,061,599
Ensembl chr 8:72,050,292...72,060,580 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 IEA MGI NCBI chr19:41,260,980...41,373,541
Ensembl chr19:41,260,816...41,373,541 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IEA MGI NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA MGI NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Plcg2 phospholipase C, gamma 2 IEA MGI NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881 		JBrowse link
G Plcl2 phospholipase C-like 2 IAGP MGI PMID:14517301 NCBI chr17:50,815,893...50,995,522
Ensembl chr17:50,816,431...50,995,512 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma IAGP MGI PMID:16129705 NCBI chr12:55,327,594...55,350,024
Ensembl chr12:55,325,776...55,349,783 		JBrowse link
G Prkcb protein kinase C, beta IAGP MGI PMID:8670417 PMID:23552399 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:24080084 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Rnf31 ring finger protein 31 IAGP MGI PMID:23942237 NCBI chr14:55,829,199...55,841,131
Ensembl chr14:55,829,165...55,841,150 		JBrowse link
G Sema4d sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D IAGP MGI PMID:11114376 NCBI chr13:51,839,565...51,947,823
Ensembl chr13:51,839,565...51,947,783 		JBrowse link
G Sfn stratifin IAGP MGI PMID:21205887 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479 		JBrowse link
G Sh3kbp1 SH3-domain kinase binding protein 1 IAGP MGI PMID:21708930 NCBI chr  X:158,409,888...158,758,916
Ensembl chr  X:158,410,268...158,761,065 		JBrowse link
G Siae sialic acid acetylesterase IAGP MGI PMID:19103880 NCBI chr 9:37,525,117...37,559,554
Ensembl chr 9:37,466,994...37,560,951 		JBrowse link
G Spi1 Spi-1 proto-oncogene IAGP MGI PMID:16311598 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 IAGP MGI PMID:23509369 NCBI chr10:7,781,412...7,832,039
Ensembl chr10:7,781,417...7,831,994 		JBrowse link
G Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 IAGP MGI PMID:23509369 NCBI chr  X:84,617,466...84,678,075
Ensembl chr  X:84,617,628...84,678,075 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Tlr8 toll-like receptor 8 IAGP MGI PMID:20811154 NCBI chr  X:166,024,119...166,047,325
Ensembl chr  X:166,025,692...166,047,325 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IAGP MGI PMID:21341261 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Vpreb1a V-set pre-B cell surrogate light chain 1A IAGP MGI PMID:11181696 PMID:12055243 NCBI chr16:16,686,265...16,687,119
Ensembl chr16:16,686,267...16,688,707 		JBrowse link
G Vpreb1b V-set pre-B cell surrogate light chain 1B IAGP MGI PMID:11181696 PMID:12055243 NCBI chr16:17,797,314...17,799,138
Ensembl chr16:17,798,292...17,799,137 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 IAGP MGI PMID:22761313 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467 		JBrowse link
absent B-1a cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blnk B cell linker IAGP MGI PMID:10700474 NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978 		JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase IAGP MGI PMID:8890160 PMID:14634110 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:12818158 PMID:12867038 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:22213803 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622 		JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain IAGP MGI PMID:15384043 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116 		JBrowse link
G Huwe1 HECT, UBA and WWE domain containing 1 IAGP MGI PMID:22213803 NCBI chr  X:150,583,779...150,718,413
Ensembl chr  X:150,583,803...150,718,413 		JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:14758357 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:8986714 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Malt1 MALT1 paracaspase IAGP MGI PMID:14576442 NCBI chr18:65,564,010...65,612,138
Ensembl chr18:65,564,009...65,612,138 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 IAGP MGI PMID:12833156 NCBI chr19:41,260,980...41,373,541
Ensembl chr19:41,260,816...41,373,541 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:22213803 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17088
    immune system phenotype 5775
      abnormal immune system morphology 4141
        abnormal immune system cell morphology 2914
          abnormal professional antigen presenting cell morphology 941
            abnormal mature B cell morphology 338
              abnormal B-1 B cell morphology 155
                abnormal B-1a B cell morphology 82
                  decreased B-1a cell number 62
                    absent B-1a cells 11
Path 2
Term Annotations click to browse term
  mammalian phenotype 17088
    hematopoietic system phenotype 5610
      abnormal hematopoietic system morphology/development 5136
        abnormal hematopoietic cell morphology 4313
          abnormal leukocyte morphology 2895
            abnormal mononuclear cell morphology 2315
              abnormal lymphocyte morphology 1876
                abnormal lymphocyte cell number 1738
                  abnormal B cell number 715
                    abnormal mature B cell number 433
                      decreased mature B cell number 337
                        decreased B-1 B cell number 111
                          decreased B-1a cell number 62
                            absent B-1a cells 11
paths to the root