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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal dendrite morphology
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Accession:MP:0008143 term browser browse the term
Definition:any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body
Synonyms:exact_synonym: abnormal dendritic arbor;   abnormal dendritic tree
 narrow_synonym: Abnormal neuron branching
 xref: HP:0500032



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abnormal dendrite morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilk integrin-linked kinase IMP inhibition in the nucleus accumbens decreases dendrite density of medium spiny neurons RGD PMID:18602949 RGD:2301736 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
abnormal hippocampal pyramidal neuron dendrite morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shank2 SH3 and multiple ankyrin repeat domains 2 IMP RGD PMID:29970986 RGD:126790534 NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:199,169,429...199,589,394
JBrowse link
G Shank2em13Sage SH3 and multiple ankyrin repeat domains 2; ZFN induced mutant13, Sage IMP RGD PMID:29970986 RGD:126790534
abnormal motor neuron dendrite morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cplx1 complexin 1 IMP RGD PMID:31875236 RGD:127285808 NCBI chr14:1,184,677...1,216,392 JBrowse link
increased dendritic spine density term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twf1 twinfilin actin-binding protein 1 IMP RGD PMID:33963280 RGD:596938166 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5421
    nervous system phenotype 380
      abnormal nervous system morphology 217
        abnormal neuron morphology 71
          abnormal neurite morphology 16
            abnormal dendrite morphology 8
              abnormal Purkinje cell dendrite morphology 1
              abnormal dendrite arborization pattern 0
              abnormal dendritic spine morphology + 1
              abnormal dentate gyrus neuron dendrite morphology 0
              abnormal motor neuron dendrite morphology 1
              abnormal pyramidal neuron dendrite morphology + 3
              abnormal retina ganglion cell dendrite morphology 0
paths to the root