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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal pituitary intermediate lobe morphology
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Accession:MP:0008130 term browser browse the term
Definition:any structural anomaly of the thin boundary between the adenohypophysis and neurohypophysis of the pituitary that produces melanocyte stimulating hormone (MSH); this area is small or absent in mammalian adults
Synonyms:exact_synonym: Pars intermedia;   intermediate part of adenohypophysis



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abnormal pituitary intermediate lobe morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin dependent kinase inhibitor 1B IAGP MGI PMID:8646779 PMID:9744866 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C IAGP MGI PMID:9744866 NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 IAGP MGI PMID:20103739 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:9671308 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box IAGP MGI PMID:12907761 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086
JBrowse link
abnormal melanotroph morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 IAGP MGI PMID:9717839 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 IAGP MGI PMID:18396135 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898
JBrowse link
absent pituitary intermediate lobe term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Emx1 empty spiracles homeobox 1 IAGP MGI PMID:17426285 NCBI chr 6:85,164,913...85,181,445
Ensembl chr 6:85,164,420...85,181,444
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IAGP MGI PMID:17426285 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Hes5 hes family bHLH transcription factor 5 IAGP MGI PMID:17426285 NCBI chr 4:155,042,358...155,046,829
Ensembl chr 4:155,045,380...155,046,828
JBrowse link
G Lhx3 LIM homeobox protein 3 IAGP MGI PMID:8638120 PMID:9865699 NCBI chr 2:26,090,224...26,098,261
Ensembl chr 2:26,090,224...26,098,301
JBrowse link
enlarged pituitary intermediate lobe term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 IAGP MGI PMID:9140068 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
pituitary intermediate lobe hyperplasia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin dependent kinase inhibitor 1B IAGP MGI PMID:8646779 PMID:8646780 PMID:9744866 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C IAGP MGI PMID:9744866 NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386
JBrowse link
G Drd2 dopamine receptor D2 IAGP MGI PMID:9247268 PMID:9717839 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:9671308 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Tpx2 TPX2, microtubule-associated IAGP MGI PMID:22266221 NCBI chr 2:152,689,859...152,737,241
Ensembl chr 2:152,689,884...152,737,241
JBrowse link
pituitary intermediate lobe hypoplasia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 IAGP MGI PMID:9247269 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
JBrowse link
small pituitary intermediate lobe term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irs2 insulin receptor substrate 2 IAGP MGI PMID:11812758 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Lhx3 LIM homeobox protein 3 IAGP MGI PMID:16859901 NCBI chr 2:26,090,224...26,098,261
Ensembl chr 2:26,090,224...26,098,301
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16963
    endocrine/exocrine gland phenotype 3451
      abnormal gland morphology 3210
        abnormal endocrine gland morphology 1352
          abnormal neuroendocrine gland morphology 177
            abnormal pituitary gland morphology 151
              abnormal pituitary intermediate lobe morphology 13
                abnormal melanotroph morphology 2
                absent pituitary intermediate lobe 4
                enlarged pituitary intermediate lobe + 5
                small pituitary intermediate lobe + 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 16963
    nervous system phenotype 4640
      abnormal nervous system morphology 3672
        abnormal brain morphology 2143
          abnormal forebrain morphology 1358
            abnormal diencephalon morphology 354
              abnormal pituitary gland morphology 151
                abnormal pituitary intermediate lobe morphology 13
                  abnormal melanotroph morphology 2
                  absent pituitary intermediate lobe 4
                  enlarged pituitary intermediate lobe + 5
                  small pituitary intermediate lobe + 3
paths to the root