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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased plasmacytoid dendritic cell number
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Accession:MP:0008124 term browser browse the term
Definition:reduced number of phagocytic dendritic cells that are morphologically similar to plasma cells, but do not express B lineage markers, and produce large amounts of alpha/beta interferons (IFN-/) in response to viral and bacterial stimuli
Synonyms:exact_synonym: decreased DC2 cell number;   decreased T-associated plasma cells cell number;   decreased lymphoid dendritic cell number;   decreased pDC cell number;   decreased plasmacytoid T cell number;   decreased plasmacytoid monocytes cell number;   reduced DC2 cell number;   reduced T-associated plasma cells cell number;   reduced lymphoid dendritic cell number;   reduced pDC cell number;   reduced plasmacytoid T cell number;   reduced plasmacytoid dendritic cell number;   reduced plasmacytoid monocytes cell number



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5380
    immune system phenotype 495
      abnormal immune system morphology 188
        abnormal immune system cell morphology 148
          abnormal leukocyte morphology 148
            abnormal leukocyte cell number 135
              decreased leukocyte cell number 90
                decreased plasmacytoid dendritic cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    hematopoietic system phenotype 244
      abnormal hematopoietic system morphology/development 224
        abnormal hematopoietic cell morphology 180
          abnormal hematopoietic cell number 142
            abnormal leukocyte cell number 135
              abnormal dendritic cell number 3
                abnormal plasmacytoid dendritic cell number 0
                  decreased plasmacytoid dendritic cell number 0
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