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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased Langerhans cell number
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Accession:MP:0008119 term browser browse the term
Definition:reduction in the number of stellate dendritic cells of myeloid origin, that appear clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus
Synonyms:exact_synonym: decreased number of Langerhans cells;   reduced Langerhans cell number;   reduced number of Langerhans cells



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decreased Langerhans cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:30249809 RGD:41404725 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf1rtm(EGFP)Tset colony stimulating factor 1 receptor; target mutant, Tset IMP RGD PMID:30249809 RGD:41404725

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal hematopoietic cell number 145
            decreased hematopoietic cell number 96
              decreased dendritic cell number 3
                decreased myeloid dendritic cell number 3
                  decreased Langerhans cell number 3
                    absent Langerhans cell 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal leukocyte morphology 154
            abnormal myeloid leukocyte morphology 70
              abnormal phagocyte morphology 47
                abnormal mononuclear phagocyte morphology 42
                  abnormal myeloid dendritic cell morphology 3
                    abnormal myeloid dendritic cell number 3
                      decreased myeloid dendritic cell number 3
                        decreased Langerhans cell number 3
                          absent Langerhans cell 0
paths to the root