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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal granulocyte differentiation
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Accession:MP:0008111 term browser browse the term
Definition:atypical production of or inability to produce leukocytes that have abundant granules in the cytoplasm, including basophils, neutrophils, and eosinophils
Synonyms:exact_synonym: abnormal granulopoiesis



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abnormal granulocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 a disintegrin and metallopeptidase domain 10 IAGP MGI PMID:22042698 NCBI chr 9:70,586,133...70,687,511
Ensembl chr 9:70,586,279...70,687,511
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon IAGP MGI PMID:9371821 NCBI chr14:54,947,823...54,949,604
Ensembl chr14:54,947,817...54,949,631
JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:29202466 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351
JBrowse link
G Csf3r colony stimulating factor 3 receptor IAGP MGI PMID:22042698 NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IAGP MGI PMID:8036519 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:20305640 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211
JBrowse link
G Gfi1 growth factor independent 1 transcription repressor IAGP MGI PMID:11810106 NCBI chr 5:107,864,521...107,873,671
Ensembl chr 5:107,864,523...107,873,902
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22699452 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:12871645 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926
JBrowse link
G Il10rb interleukin 10 receptor, beta IAGP MGI PMID:9463407 NCBI chr16:91,203,166...91,222,718
Ensembl chr16:91,203,052...91,222,722
JBrowse link
G Il17ra interleukin 17 receptor A IAGP MGI PMID:11514607 NCBI chr 6:120,440,143...120,460,692
Ensembl chr 6:120,440,208...120,464,520
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IAGP MGI PMID:9620849 NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229
JBrowse link
G Jak2 Janus kinase 2 IAGP MGI PMID:29202466 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Kmt2e lysine (K)-specific methyltransferase 2E IAGP MGI PMID:18854576 NCBI chr 5:23,638,034...23,709,233
Ensembl chr 5:23,639,439...23,709,233
JBrowse link
G Lbr lamin B receptor IAGP MGI PMID:18621876 NCBI chr 1:181,642,880...181,669,933
Ensembl chr 1:181,642,900...181,670,611
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:7590249 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Npm1 nucleophosmin 1 IAGP MGI PMID:23226219 NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206
JBrowse link
G Nras neuroblastoma ras oncogene IAGP MGI PMID:22876308 NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230
JBrowse link
G Plcd1 phospholipase C, delta 1 IAGP MGI PMID:22805570 NCBI chr 9:118,900,595...118,922,570
Ensembl chr 9:118,900,595...118,922,570
JBrowse link
G Plek2 pleckstrin 2 IAGP MGI PMID:29202466 NCBI chr12:78,935,465...78,955,166
Ensembl chr12:78,935,465...78,953,738
JBrowse link
G Plscr1 phospholipid scramblase 1 IAGP MGI PMID:12010804 NCBI chr 9:92,132,265...92,154,034
Ensembl chr 9:92,131,803...92,154,331
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IAGP MGI PMID:11163182 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
JBrowse link
G Rac2 Rac family small GTPase 2 IAGP MGI PMID:10072071 NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
JBrowse link
G Runx1 runt related transcription factor 1 IAGP MGI PMID:16081688 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Sele selectin, endothelial cell IAGP MGI PMID:8598043 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Selp selectin, platelet IAGP MGI PMID:8598043 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Senp1 SUMO1/sentrin specific peptidase 1 IAGP MGI PMID:20457756 NCBI chr15:97,936,625...97,991,625
Ensembl chr15:97,936,625...97,991,625
JBrowse link
G Sh2b3 SH2B adaptor protein 3 IAGP MGI PMID:12070287 NCBI chr 5:121,953,544...121,975,706
Ensembl chr 5:121,953,551...121,975,709
JBrowse link
G Sin3b transcriptional regulator, SIN3B (yeast) IAGP MGI PMID:18332431 NCBI chr 8:73,449,898...73,484,831
Ensembl chr 8:73,449,913...73,484,829
JBrowse link
G Socs3 suppressor of cytokine signaling 3 IAGP MGI PMID:14975238 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Spi1 Spi-1 proto-oncogene IAGP MGI PMID:15867096 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101
JBrowse link
abnormal eosinophil differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpe CCAAT/enhancer binding protein epsilon IAGP MGI PMID:9371821 NCBI chr14:54,947,823...54,949,604
Ensembl chr14:54,947,817...54,949,631
JBrowse link
G Siglecf sialic acid binding Ig-like lectin F IAGP MGI PMID:17272508 NCBI chr 7:43,000,496...43,008,899
Ensembl chr 7:43,000,765...43,008,955
JBrowse link
abnormal mast cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Commd10 COMM domain containing 10 IAGP MGI PMID:24204913 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351
JBrowse link
G Gab2 growth factor receptor bound protein 2-associated protein 2 IAGP MGI PMID:11861309 NCBI chr 7:96,730,958...96,958,158
Ensembl chr 7:96,730,793...96,958,153
JBrowse link
G Mcemp1 mast cell expressed membrane protein 1 IAGP MGI PMID:37041174 NCBI chr 8:3,715,754...3,718,916
Ensembl chr 8:3,715,754...3,719,259
JBrowse link
G Ndst2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 IAGP MGI PMID:19109198 NCBI chr14:20,773,798...20,784,638
Ensembl chr14:20,773,798...20,784,630
JBrowse link
G Patz1 POZ (BTB) and AT hook containing zinc finger 1 IAGP MGI PMID:24204913 NCBI chr11:3,239,131...3,259,083
Ensembl chr11:3,238,874...3,259,083
JBrowse link
G Pla2g3 phospholipase A2, group III IAGP MGI PMID:23624557 NCBI chr11:3,438,158...3,449,346
Ensembl chr11:3,438,284...3,449,350
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) IAGP MGI PMID:10220374 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Stat5a signal transducer and activator of transcription 5A IAGP MGI PMID:12714518 PMID:15947484 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
JBrowse link
G Stat5b signal transducer and activator of transcription 5B IAGP MGI PMID:12714518 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550
JBrowse link
G Tpsab1 tryptase alpha/beta 1 IAGP MGI PMID:19109198 NCBI chr17:25,562,219...25,564,536
Ensembl chr17:25,562,212...25,564,541
JBrowse link
G Tpsb2 tryptase beta 2 IAGP MGI PMID:19109198 NCBI chr17:25,585,282...25,587,070
Ensembl chr17:25,585,170...25,588,079
JBrowse link
abnormal neutrophil differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpe CCAAT/enhancer binding protein epsilon IAGP MGI PMID:9371821 NCBI chr14:54,947,823...54,949,604
Ensembl chr14:54,947,817...54,949,631
JBrowse link
G Csf3r colony stimulating factor 3 receptor IAGP MGI PMID:9639496 NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233
JBrowse link
G Git2 GIT ArfGAP 2 IAGP MGI PMID:16715100 NCBI chr 5:114,865,469...114,912,647
Ensembl chr 5:114,865,468...114,913,578
JBrowse link
G Kmt2e lysine (K)-specific methyltransferase 2E IAGP MGI PMID:18854576 NCBI chr 5:23,638,034...23,709,233
Ensembl chr 5:23,639,439...23,709,233
JBrowse link
G Lbr lamin B receptor IAGP MGI PMID:17403717 NCBI chr 1:181,642,880...181,669,933
Ensembl chr 1:181,642,900...181,670,611
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:18278031 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mecom MDS1 and EVI1 complex locus IAGP MGI PMID:17029558 NCBI chr 3:30,005,445...30,563,937
Ensembl chr 3:30,005,445...30,602,157
JBrowse link
G Mef2c myocyte enhancer factor 2C IAGP MGI PMID:18278031 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199
JBrowse link
G Mir223 microRNA 223 IAGP MGI PMID:18278031 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532
JBrowse link
G Plscr1 phospholipid scramblase 1 IAGP MGI PMID:12010804 NCBI chr 9:92,132,265...92,154,034
Ensembl chr 9:92,131,803...92,154,331
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:19109567 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
JBrowse link
G Spi1 Spi-1 proto-oncogene IAGP MGI PMID:8896458 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101
JBrowse link
G Stat5a signal transducer and activator of transcription 5A IAGP MGI PMID:19779039 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
JBrowse link
G Stat5b signal transducer and activator of transcription 5B IAGP MGI PMID:19779039 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 IAGP MGI PMID:19109567 NCBI chr 3:100,732,775...100,805,555
Ensembl chr 3:100,732,775...100,804,238
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16931
    cellular phenotype 5399
      abnormal cell physiology 4867
        abnormal cell differentiation 1058
          abnormal granulocyte differentiation 49
            abnormal eosinophil differentiation 2
            abnormal mast cell differentiation 11
            abnormal neutrophil differentiation 15
Path 2
Term Annotations click to browse term
  mammalian phenotype 16931
    hematopoietic system phenotype 5533
      abnormal hematopoietic system morphology/development 5064
        abnormal hematopoietic cell morphology 4231
          abnormal blood cell morphology 3177
            abnormal hemopoiesis 1155
              abnormal definitive hematopoiesis 1128
                abnormal leukopoiesis 869
                  abnormal myelopoiesis 166
                    abnormal granulocyte differentiation 49
                      abnormal eosinophil differentiation 2
                      abnormal mast cell differentiation 11
                      abnormal neutrophil differentiation 15
paths to the root