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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal memory B cell number
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Accession:MP:0008093 term browser browse the term
Definition:anomaly in the number of distinctly differentiated long-lived B cells that are readily activated upon reencounter of an antigenic determinant; memory B cells differentiate from antigen-activated B cells which have been selected for expression of higher affinity immunoglobulin


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abnormal memory B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 antigen IAGP MGI PMID:14563324 PMID:14715907 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061 		JBrowse link
G Icos inducible T cell co-stimulator IAGP MGI PMID:17549732 NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479 		JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein IAGP MGI PMID:14715907 NCBI chr10:76,304,736...76,351,693
Ensembl chr10:76,304,761...76,351,691 		JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain IAGP MGI PMID:14563324 NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497 		JBrowse link
G Rel reticuloendotheliosis oncogene IAGP MGI PMID:9862367 NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
absent memory B cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase IAGP MGI PMID:22117047 NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:22117047 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:20929728 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 (G1m marker) IAGP MGI PMID:9103199 NCBI chr12:113,290,161...113,294,143
Ensembl chr12:113,288,860...113,294,143 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 IAGP MGI PMID:20929728 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
decreased memory B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 antigen IAGP MGI PMID:8967951 NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:20929728 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:30337470 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Jak3 Janus kinase 3 IEA MGI NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 IAGP MGI PMID:20929728 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Tlr4 toll-like receptor 4 IEA MGI NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
increased memory B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 antigen IAGP MGI PMID:33336366 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:21493594 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) IAGP MGI PMID:18925577
G Jak3 Janus kinase 3 IEA MGI NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Mir148a microRNA 148a IAGP MGI PMID:33336366 NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:21493594 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16963
    immune system phenotype 5709
      abnormal immune system morphology 4077
        abnormal immune system cell morphology 2842
          abnormal professional antigen presenting cell morphology 934
            abnormal mature B cell morphology 334
              abnormal memory B cell morphology 24
                abnormal memory B cell number 18
                  decreased memory B cell number + 10
                  increased memory B cell number 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 16963
    immune system phenotype 5709
      abnormal immune system morphology 4077
        abnormal immune system cell morphology 2842
          abnormal leukocyte morphology 2821
            abnormal mononuclear cell morphology 2275
              abnormal lymphocyte morphology 1842
                abnormal B cell morphology 793
                  abnormal mature B cell morphology 334
                    abnormal memory B cell morphology 24
                      abnormal memory B cell number 18
                        decreased memory B cell number + 10
                        increased memory B cell number 6
paths to the root