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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T-helper 2 cell differentiation
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Accession:MP:0008092 term browser browse the term
Definition:atypical production of or inability to produce the type of T-helper cell whose cytokine production promotes defense against extracellular parasites and humoral immune responses typical of allergy
Synonyms:exact_synonym: abnormal Th2 cell differentiation;   abnormal helper T cell type 2 cell differentiation;   abnormal helper T lymphocyte type 2 cell differentiation


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abnormal T-helper 2 cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper transcription factor, ATF-like IAGP MGI PMID:20421391 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 IAGP MGI PMID:19881507 NCBI chr 6:145,803,969...145,811,146
Ensembl chr 6:145,803,969...145,811,284 		JBrowse link
G C3ar1 complement component 3a receptor 1 IAGP MGI PMID:12421977 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:16751370 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cblb Casitas B-lineage lymphoma b IAGP MGI PMID:19009524 NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411 		JBrowse link
G Cish cytokine inducible SH2-containing protein IAGP MGI PMID:23727894 NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983 		JBrowse link
G Col10a1 collagen, type X, alpha 1 IAGP MGI PMID:22692895 NCBI chr10:34,265,977...34,273,081
Ensembl chr10:34,265,977...34,273,081 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:24135136 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Icosl icos ligand IAGP MGI PMID:12833154 NCBI chr10:77,904,921...77,915,359
Ensembl chr10:77,905,136...77,919,747 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:16778988 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12b interleukin 12b IAGP MGI PMID:16778988 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:9768762 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il17ra interleukin 17 receptor A IAGP MGI PMID:20154671 NCBI chr 6:120,440,143...120,460,692
Ensembl chr 6:120,440,208...120,464,520 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:18719110 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Itch itchy, E3 ubiquitin protein ligase IAGP MGI PMID:24135136 NCBI chr 2:154,975,401...155,068,775
Ensembl chr 2:154,975,429...155,068,775 		JBrowse link
G Itk IL2 inducible T cell kinase IAGP MGI PMID:19009524 NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 IAGP MGI PMID:21983831 NCBI chr17:80,887,942...81,039,118
Ensembl chr17:80,887,941...81,035,914 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA MGI NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IEA MGI NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Nbr1 NBR1, autophagy cargo receptor IAGP MGI PMID:20808283 NCBI chr11:101,442,933...101,472,777
Ensembl chr11:101,442,975...101,472,777 		JBrowse link
G Pbrm1 polybromo 1 IAGP MGI PMID:22336179 NCBI chr14:30,741,095...30,843,549
Ensembl chr14:30,741,095...30,843,549 		JBrowse link
G Pgap3 post-GPI attachment to proteins 3 IAGP MGI PMID:23864655 NCBI chr11:98,279,498...98,292,022
Ensembl chr11:98,279,503...98,291,316 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IAGP MGI PMID:15137944 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 IAGP MGI PMID:19047684 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 IAGP MGI PMID:24792914 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:8602264 PMID:8624821 PMID:18719110 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:20808283 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Tslp thymic stromal lymphopoietin IAGP MGI PMID:22585305 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16962
    immune system phenotype 5703
      abnormal immune system morphology 4076
        abnormal immune system development 912
          abnormal leukopoiesis 870
            abnormal lymphopoiesis 747
              abnormal T cell differentiation 489
                abnormal CD4-positive T cell differentiation 108
                  abnormal T-helper 2 cell differentiation 28
Path 2
Term Annotations click to browse term
  mammalian phenotype 16962
    immune system phenotype 5703
      abnormal immune system morphology 4076
        abnormal immune system cell morphology 2841
          abnormal leukocyte morphology 2820
            abnormal mononuclear cell morphology 2274
              abnormal lymphocyte morphology 1841
                abnormal T cell morphology 1172
                  abnormal effector T cell morphology 855
                    abnormal CD4-positive, alpha beta T cell morphology 605
                      abnormal CD4-positive helper T cell morphology 153
                        abnormal T-helper 2 cell morphology 57
                          abnormal T-helper 2 cell differentiation 28
paths to the root