decreased T-helper 2 cell number - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	decreased T-helper 2 cell number	go back to main search page
Accession:	MP:0008091	browse the term
Definition:	reduction in the number of the type of T-helper cell whose cytokine production promotes defense against extracellular parasites and humoral immune responses typical of allergy
Synonyms:	exact_synonym:	decreased Th2 cell number; decreased helper T cell type 2 cell number; decreased helper T lymphocyte type 2 cell number; reduced T helper 2 cell number; reduced Th2 cell number; reduced helper T cell type 2 cell number; reduced helper T lymphocyte type 2 cell number

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Genes (10)

decreased T-helper 2 cell number

term browser

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

chitinase-like 1

NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919

G

Epstein-Barr virus induced gene 3

NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022

G

GATA binding protein 3

NCBI chr 2:9,861,889...9,892,762
Ensembl chr 2:9,861,889...9,894,845

G

interleukin 13

NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529

G

interleukin 25

NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294

G

interleukin 4 receptor, alpha

NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646

G

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein

NCBI chr 7:125,982,025...125,995,966
Ensembl chr 7:125,982,026...125,995,909

G

programmed cell death 1

NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278

G

phosphoglycerate mutase 1

NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099

G

signal transducer and activator of transcription 6

NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	16233
immune system phenotype	5376
abnormal immune system morphology	3802
abnormal immune system cell morphology	2666
abnormal leukocyte morphology	2645
abnormal leukocyte cell number	2367
decreased leukocyte cell number	1564
decreased lymphocyte cell number	1227
decreased T cell number	755
decreased T-helper cell number	43
decreased T-helper 2 cell number	10
Path 2
Term	Annotations
mammalian phenotype	16233
immune system phenotype	5376
abnormal immune system morphology	3802
abnormal immune system cell morphology	2666
abnormal leukocyte morphology	2645
abnormal mononuclear cell morphology	2159
abnormal lymphocyte morphology	1749
abnormal T cell morphology	1125
abnormal effector T cell morphology	818
abnormal CD4-positive, alpha beta T cell morphology	590
abnormal CD4-positive helper T cell morphology	144
abnormal T-helper 2 cell morphology	57
abnormal T-helper 2 cell number	25
decreased T-helper 2 cell number	10

paths to the root