Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal T-helper 2 cell number
go back to main search page
Accession:MP:0008089 term browser browse the term
Definition:anomaly in the number of the type of T-helper cell whose cytokine production promotes defense against extracellular parasites and humoral immune responses typical of allergy
Synonyms:exact_synonym: T helper 2 cell number abnormalities;   Th2 cell number abnormalities;   abnormal TH2 cell number;   abnormal helper T cell type 2 cell number;   abnormal helper T lymphocyte type 2 cell number



show annotations for term's descendants           Sort by:
abnormal T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chi3l1 chitinase 3 like 1 IAGP MGI PMID:19414556 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919
JBrowse link
decreased T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chi3l1 chitinase 3 like 1 IAGP MGI PMID:19414556 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919
JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 IAGP MGI PMID:12482940 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022
JBrowse link
G Gata3 GATA binding protein 3 IAGP MGI PMID:15475959 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845
JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:9768762 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il25 interleukin 25 IAGP MGI PMID:25888259 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294
JBrowse link
G Il4ra interleukin 4 receptor, alpha IAGP MGI PMID:21460847 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Nfatc2ip nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein IAGP MGI PMID:20133688 NCBI chr 7:125,982,025...125,995,909
Ensembl chr 7:125,982,026...125,995,909
JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278
JBrowse link
G Pgam1 phosphoglycerate mutase 1 IAGP MGI PMID:32709928 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099
JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:21460847 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
increased T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 a disintegrin and metallopeptidase domain 17 IAGP MGI PMID:25902485 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:9541503 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Egfr epidermal growth factor receptor IAGP MGI PMID:25902485 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 IAGP MGI PMID:18066066 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912
JBrowse link
G Il17b interleukin 17B IAGP MGI PMID:25888259 NCBI chr18:61,821,006...61,825,609
Ensembl chr18:61,817,958...61,825,609
JBrowse link
G Irf1 interferon regulatory factor 1 IAGP MGI PMID:9379011 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Lat linker for activation of T cells IAGP MGI PMID:12065839 PMID:23793062 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IAGP MGI PMID:34420035 NCBI chr18:70,701,298...70,761,769
Ensembl chr18:70,701,260...70,759,202
JBrowse link
G Mir155 microRNA 155 IAGP MGI PMID:17463290 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:14764732 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 IAGP MGI PMID:22547705 NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356
JBrowse link
G Polb polymerase (DNA directed), beta IAGP MGI PMID:24388753 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 IAGP MGI PMID:19107198 NCBI chr 5:103,573,058...103,746,227
Ensembl chr 5:103,573,058...103,746,169
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IAGP MGI PMID:25902485 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Tbx21 T-box 21 IAGP MGI PMID:11786644 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16659
    hematopoietic system phenotype 5449
      abnormal hematopoietic system morphology/development 4992
        abnormal hematopoietic cell morphology 4177
          abnormal hematopoietic cell number 3002
            abnormal leukocyte cell number 2494
              abnormal lymphocyte cell number 1671
                abnormal T cell number 1054
                  abnormal alpha-beta T cell number 684
                    abnormal CD4-positive, alpha-beta T cell number 514
                      abnormal T-helper 2 cell number 25
                        decreased T-helper 2 cell number 10
                        increased T-helper 2 cell number 15
Path 2
Term Annotations click to browse term
  mammalian phenotype 16659
    hematopoietic system phenotype 5449
      abnormal hematopoietic system morphology/development 4992
        abnormal hematopoietic cell morphology 4177
          abnormal leukocyte morphology 2778
            abnormal mononuclear cell morphology 2235
              abnormal lymphocyte morphology 1808
                abnormal T cell morphology 1149
                  abnormal alpha-beta T cell morphology 869
                    abnormal CD4-positive, alpha beta T cell morphology 597
                      abnormal CD4-positive helper T cell morphology 146
                        abnormal T-helper 2 cell morphology 57
                          abnormal T-helper 2 cell number 25
                            decreased T-helper 2 cell number 10
                            increased T-helper 2 cell number 15
paths to the root