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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T-helper 2 cell number
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Accession:MP:0008089 term browser browse the term
Definition:anomaly in the number of the type of T-helper cell whose cytokine production promotes defense against extracellular parasites and humoral immune responses typical of allergy
Synonyms:exact_synonym: T helper 2 cell number abnormalities;   Th2 cell number abnormalities;   abnormal TH2 cell number;   abnormal helper T cell type 2 cell number;   abnormal helper T lymphocyte type 2 cell number


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increased T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BB.SHR-(D6Rat184-D6Rat3)/K IAGP compared to BB/OK RGD PMID:11327715 RGD:619685 NCBI chr 6:116,506,292...138,922,889 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5380
    hematopoietic system phenotype 244
      abnormal hematopoietic system morphology/development 224
        abnormal hematopoietic cell morphology 180
          abnormal hematopoietic cell number 142
            abnormal leukocyte cell number 135
              abnormal lymphocyte cell number 93
                abnormal T cell number 63
                  abnormal alpha-beta T cell number 19
                    abnormal CD4-positive, alpha-beta T cell number 13
                      abnormal T-helper 2 cell number 1
                        decreased T-helper 2 cell number 0
                        increased T-helper 2 cell number 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    hematopoietic system phenotype 244
      abnormal hematopoietic system morphology/development 224
        abnormal hematopoietic cell morphology 180
          abnormal leukocyte morphology 148
            abnormal mononuclear cell morphology 121
              abnormal lymphocyte morphology 99
                abnormal T cell morphology 69
                  abnormal alpha-beta T cell morphology 34
                    abnormal CD4-positive, alpha beta T cell morphology 17
                      abnormal CD4-positive helper T cell morphology 1
                        abnormal T-helper 2 cell morphology 1
                          abnormal T-helper 2 cell number 1
                            decreased T-helper 2 cell number 0
                            increased T-helper 2 cell number 1
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