decreased T helper 1 cell number - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	decreased T helper 1 cell number	go back to main search page
Accession:	MP:0008087	browse the term
Definition:	reduced number of the subset of the type of T-helper cell whose cytokine production favors cellular immune responses and delayed type hypersensitivity
Synonyms:	exact_synonym:	decreased Th1 cell number; decreased helper T cell type 1 cell number; decreased helper T lymphocyte type 1 cell number; reduced T helper 1 cell number; reduced Th1 cell number; reduced helper T cell type 1 cell number; reduced helper T lymphocyte type 1 cell number

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Genes (9)

decreased T helper 1 cell number

term browser

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CD274 antigen

NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495

G

CD4 antigen

NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184

G

CD5 antigen

NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366

G

interleukin 1 receptor, type I

NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417

G

natural killer cell group 7 sequence

NCBI chr 7:43,086,562...43,087,670
Ensembl chr 7:43,086,497...43,087,673

G

solute carrier family 1 (neutral amino acid transporter), member 5

NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199

G

T-box 21

NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157

G

V-set and immunoglobulin domain containing 4

NCBI chr X:95,290,807...95,337,044
Ensembl chr X:95,290,809...95,337,044

G

zinc finger, RAN-binding domain containing 1

NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	16242
immune system phenotype	5382
abnormal immune system morphology	3803
abnormal immune system cell morphology	2667
abnormal leukocyte morphology	2646
abnormal leukocyte cell number	2368
decreased leukocyte cell number	1566
decreased lymphocyte cell number	1228
decreased T cell number	756
decreased T-helper cell number	43
decreased T helper 1 cell number	9
Path 2
Term	Annotations
mammalian phenotype	16242
immune system phenotype	5382
abnormal immune system morphology	3803
abnormal immune system cell morphology	2667
abnormal leukocyte morphology	2646
abnormal mononuclear cell morphology	2161
abnormal lymphocyte morphology	1750
abnormal T cell morphology	1126
abnormal effector T cell morphology	818
abnormal CD4-positive, alpha beta T cell morphology	590
abnormal CD4-positive helper T cell morphology	144
abnormal T-helper 1 cell morphology	65
abnormal T-helper 1 cell number	32
decreased T helper 1 cell number	9

paths to the root