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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased single-positive T cell number
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Accession:MP:0008083 term browser browse the term
Definition:reduced number of T cells bearing either CD4 or CD8 markers on their surface
Synonyms:exact_synonym: reduced single positive T cell number


show annotations for term's descendants           Sort by:
decreased single-positive T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase IAGP MGI PMID:2065353 NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239 		JBrowse link
G Actb actin, beta IAGP MGI PMID:23544080 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509 		JBrowse link
G Aff1 AF4/FMR2 family, member 1 IAGP MGI PMID:10887138 NCBI chr 5:103,840,307...104,003,188
Ensembl chr 5:103,840,240...104,003,188 		JBrowse link
G Atm ataxia telangiectasia mutated IAGP MGI PMID:26310626 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G B2m beta-2 microglobulin IAGP MGI PMID:15446308 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G Bcap31 B cell receptor associated protein 31 IAGP MGI PMID:28333124 NCBI chr  X:72,729,784...72,761,421
Ensembl chr  X:72,729,784...72,759,781 		JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:10881179 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Bsg basigin IAGP MGI PMID:24391450 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Caml calcium modulating ligand IAGP MGI PMID:16111633 NCBI chr13:55,770,818...55,780,229
Ensembl chr13:55,770,818...55,780,224 		JBrowse link
G Cbl Casitas B-lineage lymphoma IAGP MGI PMID:16211006 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346 		JBrowse link
G Cd247 CD247 antigen IAGP MGI PMID:8223444 PMID:8223445 NCBI chr 1:165,607,514...165,698,722
Ensembl chr 1:165,616,250...165,704,846 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IAGP MGI PMID:16043517 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Ciita class II transactivator IAGP MGI PMID:15446308 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Cops5 COP9 signalosome subunit 5 IAGP MGI PMID:18268034 NCBI chr 1:10,094,825...10,108,384
Ensembl chr 1:10,094,826...10,108,393 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 IAGP MGI PMID:15263024 NCBI chr 5:109,702,575...109,707,301
Ensembl chr 5:109,702,575...109,706,859 		JBrowse link
G Ctcf CCCTC-binding factor IAGP MGI PMID:18923423 NCBI chr 8:106,351,135...106,409,554
Ensembl chr 8:106,363,200...106,409,554 		JBrowse link
G Dclre1c DNA cross-link repair 1C IEA MGI NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IEA MGI NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IEA MGI NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Dsg3 desmoglein 3 IAGP MGI PMID:25542773 NCBI chr18:20,643,331...20,674,367
Ensembl chr18:20,643,331...20,680,516 		JBrowse link
G Elk4 ELK4, member of ETS oncogene family IAGP MGI PMID:14770179 NCBI chr 1:131,935,129...131,954,186
Ensembl chr 1:131,935,345...131,960,350 		JBrowse link
G Ep300 E1A binding protein p300 IAGP MGI PMID:16428436 NCBI chr15:81,470,329...81,536,278
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Fadd Fas associated via death domain IAGP MGI PMID:16116191 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200 		JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 IAGP MGI PMID:17984302 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505 		JBrowse link
G Foxn1 forkhead box N1 IAGP MGI PMID:22072979 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384 		JBrowse link
G Grap2 GRB2-related adaptor protein 2 IAGP MGI PMID:19401562 NCBI chr15:80,456,798...80,537,055
Ensembl chr15:80,456,795...80,537,055 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:15908920 PMID:20123962 PMID:20439541 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 IAGP MGI PMID:9491996 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G Hax1 HCLS1 associated X-1 IAGP MGI PMID:18288109 NCBI chr 3:89,902,753...89,906,023
Ensembl chr 3:89,902,753...89,906,087 		JBrowse link
G Hivep2 human immunodeficiency virus type I enhancer binding protein 2 IAGP MGI PMID:11668343 NCBI chr10:13,841,819...14,027,122
Ensembl chr10:13,841,819...14,027,118 		JBrowse link
G Htra2 HtrA serine peptidase 2 IAGP MGI PMID:18288109 NCBI chr 6:83,028,247...83,031,552
Ensembl chr 6:83,028,247...83,032,254 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:14499113 NCBI chr 8:23,149,221...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma IAGP MGI PMID:14499113 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il15ra interleukin 15 receptor, alpha chain IAGP MGI PMID:11777964 NCBI chr 2:11,709,992...11,738,796
Ensembl chr 2:11,710,101...11,739,128 		JBrowse link
G Il2rg interleukin 2 receptor, gamma chain IAGP MGI PMID:7697543 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861 		JBrowse link
G Il7 interleukin 7 IAGP MGI PMID:17151827 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820 		JBrowse link
G Irf3 interferon regulatory factor 3 IAGP MGI PMID:28951494 NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272 		JBrowse link
G Itgb2 integrin beta 2 IAGP MGI PMID:17119112 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Itk IL2 inducible T cell kinase IAGP MGI PMID:10213685 NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Jak3 Janus kinase 3 IEA MGI NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 IAGP MGI PMID:19380761 PMID:19401562 NCBI chr11:33,996,928...34,042,281
Ensembl chr11:33,996,920...34,042,295 		JBrowse link
G Ltbr lymphotoxin B receptor IEA MGI NCBI chr 6:125,283,534...125,291,026
Ensembl chr 6:125,283,534...125,290,848 		JBrowse link
G Map3k3 mitogen-activated protein kinase kinase kinase 3 IAGP MGI PMID:19223432 NCBI chr11:105,975,358...106,047,482
Ensembl chr11:105,975,439...106,046,272 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 IAGP MGI PMID:16940043 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 IAGP MGI PMID:19234191 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mdm4 transformed mouse 3T3 cell double minute 4 IEA MGI NCBI chr 1:132,913,843...132,958,325
Ensembl chr 1:132,887,222...132,958,299 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IAGP MGI PMID:9407039 PMID:9529315 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 IAGP MGI PMID:9407039 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A IEA MGI NCBI chr11:70,982,023...71,035,780
Ensembl chr11:70,983,062...71,035,530 		JBrowse link
G Nmt1 N-myristoyltransferase 1 IAGP MGI PMID:26423150 NCBI chr11:102,919,163...102,959,734
Ensembl chr11:102,919,016...102,959,738 		JBrowse link
G Nmt2 N-myristoyltransferase 2 IAGP MGI PMID:26423150 NCBI chr 2:3,285,249...3,329,914
Ensembl chr 2:3,285,249...3,329,914 		JBrowse link
G Noc2l NOC2 like nucleolar associated transcriptional repressor IAGP MGI PMID:25201955 NCBI chr 4:156,319,112...156,332,073
Ensembl chr 4:156,320,376...156,332,073 		JBrowse link
G Notch1 notch 1 IAGP MGI PMID:10367900 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IAGP MGI PMID:22653054 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 IAGP MGI PMID:28294127 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519 		JBrowse link
G Orai2 ORAI calcium release-activated calcium modulator 2 IAGP MGI PMID:28294127 NCBI chr 5:136,176,310...136,201,418
Ensembl chr 5:136,176,313...136,199,567 		JBrowse link
G Pknox1 Pbx/knotted 1 homeobox IAGP MGI PMID:16314502 NCBI chr17:31,783,697...31,826,665
Ensembl chr17:31,783,708...31,826,667 		JBrowse link
G Plcg1 phospholipase C, gamma 1 IAGP MGI PMID:20123962 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680 		JBrowse link
G Pnp purine-nucleoside phosphorylase IAGP MGI PMID:10859343 NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,202,694 		JBrowse link
G Pole4 polymerase (DNA-directed), epsilon 4 (p12 subunit) IAGP MGI PMID:29754823 NCBI chr 6:82,593,513...82,629,985
Ensembl chr 6:82,595,973...82,682,346 		JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform IAGP MGI PMID:12091710 NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit IAGP MGI PMID:17060460 NCBI chr 7:126,385,038...126,391,729
Ensembl chr 7:126,385,038...126,391,668 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:9768755 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Prss16 serine protease 16 (thymus) IAGP MGI PMID:19283781 NCBI chr13:22,186,346...22,193,911
Ensembl chr13:22,186,343...22,193,912 		JBrowse link
G Ptcra pre T cell antigen receptor alpha IEA MGI NCBI chr17:47,066,589...47,074,638
Ensembl chr17:47,066,589...47,074,638 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 IAGP MGI PMID:22590589 NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,597...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:19283781 PMID:19597497 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IAGP MGI PMID:22719950 NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IAGP MGI PMID:12039915 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
G Rfx5 regulatory factor X, 5 (influences HLA class II expression) IAGP MGI PMID:9491996 NCBI chr 3:94,861,355...94,868,685
Ensembl chr 3:94,861,386...94,868,872 		JBrowse link
G Rhoh ras homolog family member H IAGP MGI PMID:17119112 NCBI chr 5:66,018,092...66,054,043
Ensembl chr 5:66,018,556...66,054,043 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 IAGP MGI PMID:22815285 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882 		JBrowse link
G Runx1 runt related transcription factor 1 IAGP MGI PMID:17626615 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037 		JBrowse link
G Sell selectin, lymphocyte IEA MGI NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Septin9 septin 9 IAGP MGI PMID:23644740 NCBI chr11:117,090,487...117,253,151
Ensembl chr11:117,090,487...117,253,151 		JBrowse link
G Sgpl1 sphingosine phosphate lyase 1 IAGP MGI PMID:23544080 NCBI chr10:60,934,421...60,983,463
Ensembl chr10:60,934,421...60,983,482 		JBrowse link
G Shc1 src homology 2 domain-containing transforming protein C1 IAGP MGI PMID:12101399 NCBI chr 3:89,325,858...89,337,336
Ensembl chr 3:89,325,750...89,337,334 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 IAGP MGI PMID:18955569 NCBI chr 9:21,527,377...21,615,526
Ensembl chr 9:21,527,465...21,615,526 		JBrowse link
G Spns2 SPNS lysolipid transporter 2, sphingosine-1-phosphate IAGP MGI PMID:22723910 NCBI chr11:72,342,464...72,380,797
Ensembl chr11:72,342,464...72,380,730 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 IEA MGI NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 IAGP MGI PMID:28951494 NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA MGI NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 IAGP MGI PMID:22411629 NCBI chr18:37,773,544...37,777,257
Ensembl chr18:37,773,544...37,777,257 		JBrowse link
G Tcf7 transcription factor 7, T cell specific IAGP MGI PMID:7870176 NCBI chr11:52,137,347...52,174,211
Ensembl chr11:52,143,198...52,174,158 		JBrowse link
G Themis thymocyte selection associated IAGP MGI PMID:19597497 PMID:19597498 PMID:19620281 NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IEA MGI NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559 		JBrowse link
G Txk TXK tyrosine kinase IAGP MGI PMID:10213685 NCBI chr 5:72,853,321...72,910,337
Ensembl chr 5:72,853,321...72,910,120 		JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:9354466 PMID:14623913 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Vav2 vav 2 oncogene IAGP MGI PMID:14623913 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045 		JBrowse link
G Vav3 vav 3 oncogene IAGP MGI PMID:14623913 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014 		JBrowse link
G Was Wiskott-Aldrich syndrome IAGP MGI PMID:17878299 NCBI chr  X:7,947,705...7,956,730
Ensembl chr  X:7,947,692...7,956,737 		JBrowse link
G Wasl WASP like actin nucleation promoting factor IAGP MGI PMID:17878299 NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008 		JBrowse link
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 IAGP MGI PMID:9390689 NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286 		JBrowse link
G Zfp335 zinc finger protein 335 IAGP MGI PMID:25343476 NCBI chr 2:164,733,802...164,756,034
Ensembl chr 2:164,733,802...164,753,677 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16534
    hematopoietic system phenotype 5358
      abnormal hematopoietic system morphology/development 4899
        abnormal hematopoietic cell morphology 4076
          abnormal hematopoietic cell number 2935
            abnormal leukocyte cell number 2441
              abnormal lymphocyte cell number 1643
                decreased lymphocyte cell number 1238
                  decreased T cell number 760
                    decreased single-positive T cell number 97
Path 2
Term Annotations click to browse term
  mammalian phenotype 16534
    hematopoietic system phenotype 5358
      abnormal hematopoietic system morphology/development 4899
        abnormal hematopoietic cell morphology 4076
          abnormal leukocyte morphology 2724
            abnormal mononuclear cell morphology 2200
              abnormal lymphocyte morphology 1779
                abnormal lymphocyte cell number 1643
                  decreased lymphocyte cell number 1238
                    decreased T cell number 760
                      decreased single-positive T cell number 97
paths to the root