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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal CD4-positive T cell differentiation
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Accession:MP:0008076 term browser browse the term
Definition:atypical production of or inability to produce the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production
Synonyms:exact_synonym: abnormal CD4+ T cell differentiation


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abnormal CD4-positive T cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7b ATPase copper transporting beta IAGP RGD PMID:17434290 RGD:15036800 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Atp7bhts ATPase copper transporting beta; hepatitis IAGP RGD PMID:17434290 RGD:15036800
G Ptprk protein tyrosine phosphatase, receptor type, K IAGP RGD PMID:17434290 RGD:15036800 NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5380
    immune system phenotype 495
      abnormal immune system morphology 188
        abnormal immune system development 21
          abnormal leukopoiesis 18
            abnormal lymphopoiesis 18
              abnormal T cell differentiation 18
                abnormal CD4-positive T cell differentiation 4
                  abnormal T follicular helper cell differentiation 0
                  abnormal T-helper 1 cell differentiation 0
                  abnormal T-helper 2 cell differentiation 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    immune system phenotype 495
      abnormal immune system morphology 188
        abnormal immune system cell morphology 148
          abnormal leukocyte morphology 148
            abnormal mononuclear cell morphology 121
              abnormal lymphocyte morphology 99
                abnormal T cell morphology 69
                  abnormal alpha-beta T cell morphology 34
                    abnormal CD4-positive, alpha beta T cell morphology 17
                      abnormal CD4-positive T cell differentiation 4
                        abnormal T follicular helper cell differentiation 0
                        abnormal T-helper 1 cell differentiation 0
                        abnormal T-helper 2 cell differentiation 0
paths to the root