increased NK cell number - Ontology Report

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	increased NK cell number	go back to main search page
Accession:	MP:0008044	browse the term
Definition:	greater number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Synonyms:	exact_synonym:	increased natural killer cell number
	xref:	CL:0000623; FMA:63147; FMA:83601

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Genes (3) Strains (3)

increased NK cell number

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dpp4

dipeptidylpeptidase 4

IAGP

compared to DA/Ztm

RGD

PMID:19327106

RGD:41408336

NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901

Dpp4^DPPIV

dipeptidylpeptidase 4; DPPIV mutant

IAGP

compared to DA/Ztm

RGD

PMID:19327106

RGD:41408336

Rag2

recombination activating 2

IMP

RGD

PMID:30206106

RGD:38508903

NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5374
immune system phenotype	492
abnormal immune system morphology	187
abnormal immune system cell morphology	147
abnormal leukocyte morphology	147
abnormal leukocyte cell number	134
abnormal lymphocyte cell number	92
increased lymphocyte cell number	28
increased NK cell number	6
increased KLRG1-positive NK cell number	0
increased immature NK cell number +	0
increased mature NK cell number +	0
increased memory-marker NK cell number	0
increased uterine NK cell number	0
Path 2
Term	Annotations
mammalian phenotype	5374
immune system phenotype	492
abnormal immune system morphology	187
abnormal immune system cell morphology	147
abnormal leukocyte morphology	147
abnormal mononuclear cell morphology	120
abnormal lymphocyte morphology	98
abnormal lymphocyte cell number	92
increased lymphocyte cell number	28
increased NK cell number	6
increased KLRG1-positive NK cell number	0
increased immature NK cell number +	0
increased mature NK cell number +	0
increased memory-marker NK cell number	0
increased uterine NK cell number	0

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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MAMMALIAN PHENOTYPE - ANNOTATIONS