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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased NK cell number
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Accession:MP:0008044 term browser browse the term
Definition:greater number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Synonyms:exact_synonym: increased natural killer cell number
 xref: CL:0000623;   FMA:63147;   FMA:83601



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increased NK cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system cell morphology 154
          abnormal leukocyte morphology 154
            abnormal leukocyte cell number 138
              abnormal lymphocyte cell number 93
                increased lymphocyte cell number 28
                  increased NK cell number 6
                    increased KLRG1-positive NK cell number 0
                    increased immature NK cell number + 0
                    increased mature NK cell number + 0
                    increased memory-marker NK cell number 0
                    increased uterine NK cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system cell morphology 154
          abnormal leukocyte morphology 154
            abnormal mononuclear cell morphology 127
              abnormal lymphocyte morphology 99
                abnormal lymphocyte cell number 93
                  increased lymphocyte cell number 28
                    increased NK cell number 6
                      increased KLRG1-positive NK cell number 0
                      increased immature NK cell number + 0
                      increased mature NK cell number + 0
                      increased memory-marker NK cell number 0
                      increased uterine NK cell number 0
paths to the root