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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal myeloid dendritic cell morphology
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Accession:MP:0006173 term browser browse the term
Definition:any structural anomaly of phagocytic cells of the myeloid lineage that capture antigens in the periphery and then migrate to the lymphoid organs and secrete cytokines to initiate immune responses
Synonyms:exact_synonym: abnormal DC1 morphology


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decreased Langerhans cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:30249809 RGD:41404725 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf1rtm(EGFP)Tset colony stimulating factor 1 receptor; target mutant, Tset IMP RGD PMID:30249809 RGD:41404725
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5374
    immune system phenotype 492
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal professional antigen presenting cell morphology 33
            abnormal dendritic cell morphology 3
              abnormal myeloid dendritic cell morphology 3
                abnormal Langerhans cell morphology + 3
                abnormal myeloid dendritic cell number + 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5374
    hematopoietic system phenotype 243
      abnormal hematopoietic system morphology/development 223
        abnormal hematopoietic cell morphology 179
          abnormal leukocyte morphology 147
            abnormal myeloid leukocyte morphology 64
              abnormal phagocyte morphology 41
                abnormal mononuclear phagocyte morphology 36
                  abnormal myeloid dendritic cell morphology 3
                    abnormal Langerhans cell morphology + 3
                    abnormal myeloid dendritic cell number + 3
paths to the root